Evidence map›Paper›PMID 40909723›Full record

ArticlebioRxiv : the preprint server for biology2025

SAGA (Simplified Association Genome-wide Analyses): a user-friendly Pipeline to Democratize Genome-Wide Association Studies.

Basilio Cieza, Neetesh Pandey, Vivek Ruhela, Sarwan Ali, Giuseppe Tosto

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Basilio CiezaTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University. 630 West 168 Street, New York, NY 10032, USA.
Neetesh PandeyTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University. 630 West 168 Street, New York, NY 10032, USA.
Vivek RuhelaTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University. 630 West 168 Street, New York, NY 10032, USA.
Sarwan AliTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University. 630 West 168 Street, New York, NY 10032, USA.
Giuseppe TostoTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University. 630 West 168 Street, New York, NY 10032, USA.ORCID 0000-0001-7075-8245

Funding

Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)U19AG074865 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GOLDIE S. BYRD, William S Bush · 2022 to 2026
$55.3M
GLASS-AD: Global Latinos Sequencing Study for Alzheimer's DiseaseU01AG081817 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARTIN, EDEN R., PERICAK-VANCE, MARGARET A. · 2023 to 2025
$8.2M
Polygenic Risk Scores for Alzheimer's Disease in Hispanic/Latinx PopulationsRF1AG082009 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PARE, GUILLAUME, TOSTO, GIUSEPPE · 2023 to 2023
$1.9M
NIA NIH HHS RF1 AG082009NIA NIH HHS U01 AG081817NIA NIH HHS U19 AG074865
6 · The paper itself

Abstract

Genome-wide association studies (GWAS) have enabled clinicians and researchers to identify genetic variants linked to complex traits and diseases(1-3). However, GWAS still face several challenges, particularly regarding accessibility and reproducibility (4-6). Conducting these analyses often requires substantial bioinformatics expertise for data preprocessing, software installation, and scripting(7-10). We then developed SAGA ("

Indexed as

bashGMMATGWASManhattan plotpipelinePLINKquantile-quantile plotSAIGEsummary statisticsuser-friendly

Identifiers

PMID40909723
PMCPMC12407738

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.