Evidence map›Paper›PMID 40909681›Full record

ArticlebioRxiv : the preprint server for biology2025

The Contribution of Baseline Circulating Endocannabinoids to Individual Differences in Human Pain Sensitivity: A Quantitative Sensory Testing Study.

S A Fatemi, S S Abssy, S L Bourke, K B Murray, C Kyeremaa-Adjei, L Honigman, N Mohabir, C Sexton, M A Cormie, R Tomin and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

S A FatemiCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.
S S AbssyCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0009-0001-7044-3566
S L BourkeCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0000-0003-3995-8286
K B MurrayPharmacology and Therapeutics, University of Galway, Galway, Ireland.
C Kyeremaa-AdjeiPharmacology and Therapeutics, University of Galway, Galway, Ireland.
L HonigmanCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0000-0002-3338-4675
N MohabirCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0000-0002-4914-9485
C SextonCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0000-0002-7422-1004
M A CormieCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0009-0008-5121-9228
R TominCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0009-0003-4893-2712
I BoileauCentre for Addiction and Mental Health, Toronto, ON, Canada.ORCID 0000-0002-9901-1484
L Y AtlasNational Center For Complementary and Integrative Health, National Institutes of Health, Bethesda, MD, United States.ORCID 0000-0001-5693-4169
D P FinnPharmacology and Therapeutics, University of Galway, Galway, Ireland.ORCID 0000-0001-6186-621X
M MoayediCentre for Multimodal Sensorimotor and Pain Research, Faculty of Dentistry, University of Toronto, Toronto, Canada.ORCID 0000-0002-7324-2540

Funding

Neural and psychological mechanisms of pain perception ZIAAT000030 · NCCIH · NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH · PI ATLAS, LAUREN · 2015 to 2025
$3.8M
Intramural NIH HHS ZIA AT000030
6 · The paper itself

Abstract

The endocannabinoid (eCB) system-comprising cannabinoid receptors, eCBs (anandamide-AEA, 2-arachidonoylglycerol-2-AG) and related

Indexed as

Fatty-acid amide hydrolaseN-acylethanolaminesPainQuantitative Sensory TestingSex Differences

Identifiers

PMID40909681
PMCPMC12407723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.