Evidence map›Paper›PMID 40909657›Full record

ArticlebioRxiv : the preprint server for biology2025

Linh Huynh, Razan A Fakieh, C'Brionne Hendrix, Reid Powell, David J Reiner

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Linh HuynhCollege of Medicine, Texas A&M University, Houston TX, 77030, USA.
Razan A FakiehCollege of Medicine, Texas A&M University, Houston TX, 77030, USA.
C'Brionne HendrixCollege of Medicine, Texas A&M University, Houston TX, 77030, USA.
Reid PowellCollege of Medicine, Texas A&M University, Houston TX, 77030, USA.
David J ReinerCollege of Medicine, Texas A&M University, Houston TX, 77030, USA.ORCID 0000-0002-0344-7161

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Understanding Ras effector switching and roles of Ras>RalGEF>Ral in developmentR35GM144237 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI David Reiner · 2022 to 2026
$1.9M
Uncoupling Ral signal transduction from Exocyst functionsR03CA289854 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI REINER, DAVID · 2024 to 2025
$147k
NCI NIH HHS R03 CA289854NIGMS NIH HHS R35 GM144237NIH HHS P40 OD010440
6 · The paper itself

Abstract

Hippo signaling is a conserved regulator of tissue homeostasis across metazoans. The Ste20 family kinase Hippo/MST activates the NDR family kinase Warts/LATS to inhibit the transcriptional coactivator Yorkie/YAP/TAZ and its transcription factor partner Scalloped/TEAD. In

Indexed as

GCK-2HippoHpoMIG-15MST1MST2Sterile 20TEADWartsWtsYapYki

Identifiers

PMID40909657
PMCPMC12407797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.