Evidence map›Paper›PMID 40909400›Full record

ArticleFrontiers in psychiatry2025

The mediating role of family adaptability in the relationship between insecure attachment and family functioning in patients with major depression disorder: a cross-sectional study.

Xinlei Cheng, Xinfei Li, Jinlong Zhao, Lei Wang, Xiaoning Shi

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinlei ChengBeijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Xinfei LiInstitute of Developmental Psychology, Faculty of Psychology, Beijing Normal University, Beijing, China.
Jinlong ZhaoBeijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Lei WangBeijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Xiaoning ShiBeijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Depression ranks as the second leading cause of the global health burden; therefore, identification of its risk and influencing factors is essential to develop more effective multidimensional interventions. The aim of the present study was to analyze the mediating role of family adaptability (FA) on the relationship between insecure attachment (IA) and family functioning (FF) in patients with major depressive disorder (MDD), which currently remains unclear. It also aims to provide a theoretical reference for optimizing rehabilitation interventions. Methods: This cross-sectional study enrolled 62 patients with MDD who were admitted to a tertiary hospital in Beijing from March 2024 to December 2024. Participants completed the General Information Questionnaire, Family Assessment Device, Family Adaptability and Cohesion Evaluation Scale, and the Experiences in Close Relationships Relationship Structures Scale. The 17-item Hamilton Depression Rating Scale was also administered. Subsequently, association analysis was performed. Results: Notable correlations were observed among IA, FA, and FF in adults with MDD. Regression analysis established both IA and FA as reliable predictors of FF. Bootstrap-mediated analysis revealed that FA partially mediated the relationship between IA and FF, accounting for 35.47% of the total association. Further analysis demonstrated differential mediation proportions; FA mediated 39.36% of the association between anxious IA and FF and 42.61% of the association between avoidant IA and FF, with all mediation pathways meeting conventional thresholds for statistical significance. Conclusions: IA in adult patients with MDD negatively impacts FF, with both anxious and avoidant IA subtypes showing independent negative associations partially linked by FA. Rehabilitation strategies should prioritize multidimensional interventions targeting the enhancement of FA to improve FF and facilitate clinical recovery.

Indexed as

family adaptabilityfamily functioninginsecure attachmentmajor depressive disordersmediating

Identifiers

PMID40909400
PMCPMC12406130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.