Evidence map›Paper›PMID 40909391›Full record

Article3 Biotech2025

Cold-brewed yellow tea showed stronger inhibition on high-fat diet induced mice obesity than that hot brewed, due to higher non-ester catechins content based on metabolomic profile.

Lianbao Zheng, Yuanhang Yang, Qun Ye, Fang Wang, Xiaohong Zhang, Zhengyu Hou, Chenghui Lu, Baoming Tian, Renjie Liu, Tong Hu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lianbao ZhengCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Yuanhang YangCollege of Life Science, Sichuan Agricultural University, Ya'an, Sichuan China.
Qun YeCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Fang WangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Xiaohong ZhangLishui Institute for Quality Inspection and Testing, Lishui, China.
Zhengyu HouCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Chenghui LuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Baoming TianCollege of Food Science and Technology, Zhejiang University of Technology, Huzhou, China.
Renjie LiuZhejiang Gengshengtang Ecological Agriculture Co., Ltd, Huzhou, China.
Tong HuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Weihong ZhongCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.ORCID 0000-0002-5673-2222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effect of Mogan large-leaf yellow tea (MG-LYT) on preventing obesity. It was found that cold-brewed yellow tea has stronger anti-obesity effects in high-fat diet (HFD)-induced obese mice than hot-brewed tea, due to its higher content of non-esterified catechins, as shown by metabolomic and high-performance liquid chromatography (HPLC) analysis. Notably, epigallocatechin (EGC), a key non-ester catechin, likely enhances pancreatic lipase inhibition through allosteric modulation, which explains the greater effectiveness of cold-brewed tea. Dietary supplementation with cold-brewed MG-LYT significantly reduced HFD-induced obesity and related metabolic disorders in mice, including hepatic steatosis, dyslipidemia, and adipose accumulation, while elevating fecal short-chain fatty acid (SCFA) levels and modulating gut microbiota composition. These findings suggest that cold-brewed yellow tea may be a beneficial daily beverage for preventing obesity, improving metabolic health, and regulating gut microbiota.

Indexed as

Gut microbiotaLarge-leaf yellow teaLipase inhibitionMetabolomic

Identifiers

PMID40909391
PMCPMC12405141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.