Evidence map›Paper›PMID 40909379›Full record

ArticleJournal of surgical case reports2025

Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body.

Masakazu Matsuda, Shohei Yoshiya, Ippei Kawada, Sota Nakamura, Kazuhiro Tada, Kensaku Ito, Hidenori Koso, Yosuke Kuroda, Fumitaka Yoshizumi, Kentaro Iwaki and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Masakazu MatsudaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.ORCID https://orcid.org/0009-0002-8701-9195
Shohei YoshiyaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Ippei KawadaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Sota NakamuraDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Kazuhiro TadaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Kensaku ItoDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka-shi, Fukuoka 812-8582, Japan.
Hidenori KosoDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka-shi, Fukuoka 812-8582, Japan.
Yosuke KurodaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Fumitaka YoshizumiDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Kentaro IwakiDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Shoji HiroshigeDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Yo-Ichi YamashitaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Hideya TakeuchiDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka-shi, Fukuoka 812-8582, Japan.
Tomoharu YoshizumiDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.
Kengo FukuzawaDepartment of Surgery, Oita Red Cross Hospital, 3-2-37 Chiyomachi, Oita-shi, Oita 870-0033, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare. In most cases, hematogenous metastasis is symptomatic, including perforation or bleeding, and the prognosis is poor. A 63-year-old man had lower right abdominal pain, and small intestinal obstruction due to chronic inflammation of the foreign body was suspected on computed tomography. Blood tests revealed elevated alpha-fetoprotein (AFP). He had undergone four surgeries for HCC. Conservative treatment was administered, but there was little improvement. A segmental resection of the small intestine was performed. A type 2 tumor was found in the resected specimen, and pathological examination led to a diagnosis of HCC metastasis in the small intestine. He survived without recurrence for 10 months after surgery. When a patient with a history of HCC treatment develops intestinal obstruction or intussusception, it is necessary to consider the possibility of small intestinal metastasis, especially if there is an increase in AFP.

Indexed as

AFPhepatocellular carcinomaintestinal obstructionmetastasissmall intestine

Identifiers

PMID40909379
PMCPMC12408096

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