Evidence map›Paper›PMID 40909198›Full record

ArticleLaryngoscope investigative otolaryngology2025

Impact of Childhood Tonsillectomy on Adult Height-A Study of the UK Biobank.

Wendan Gong, Ioannis Psychogios, Yihan Hu, Shangjun Li, Wenwen Chen, Jiaming Su, Huan Song, Xue Xiao, Zhe Zhang, Yi Huang and 1 more

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wendan GongDepartment of Otolaryngology-Head & Neck Surgery First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China.
Ioannis PsychogiosUnit of Integrative Epidemiology Institute of Environmental Medicine, Karolinska Institutet Stockholm Sweden.
Yihan HuUnit of Integrative Epidemiology Institute of Environmental Medicine, Karolinska Institutet Stockholm Sweden.
Shangjun LiDepartment of Communication University of California Davis California USA.
Wenwen ChenWest China Biomedical Big Data Center West China Hospital, Sichuan University Chengdu China.
Jiaming SuDepartment of Otolaryngology-Head & Neck Surgery First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China.
Huan SongWest China Biomedical Big Data Center West China Hospital, Sichuan University Chengdu China.
Xue XiaoDepartment of Otolaryngology-Head & Neck Surgery First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China.
Zhe ZhangDepartment of Otolaryngology-Head & Neck Surgery First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China.ORCID https://orcid.org/0000-0001-8816-3194
Yi HuangKey Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumor (Guangxi Medical University), Ministry of Education Nanning Guangxi China.
Fang FangUnit of Integrative Epidemiology Institute of Environmental Medicine, Karolinska Institutet Stockholm Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Previous studies have suggested a postoperative "catch-up growth" in children undergoing tonsillectomy. Given the tonsils' crucial role in early immune development, examining long-term effects is imperative. This study aims to investigate the impact of tonsillectomy in early life on adult height and height disparity. Methods: Using data from the UK Biobank, we compared individuals with a childhood tonsillectomy to individuals without such an experience, after matching them individually by age and sex. We used standing height measured at recruitment to the UK Biobank as attained adult height, polygenic risk score (PRS) for height as a proxy for genetically determined height, and height deviation and height deficit as proxies for height disparity. We assessed the association of tonsillectomy with these outcomes, using a linear mixed-effect model or conditional logistic regression, after multivariable adjustment. Results: Individuals with a childhood tonsillectomy had a slightly higher attained adult height (mean: 169.0 cm; standard deviation [SD] 9.23) compared to their age- and sex-matched comparators (mean: 168.5 cm; SD 9.30). After multivariable adjustment, childhood tonsillectomy was associated with a marginally higher attained adult height ( Conclusions: Individuals with childhood tonsillectomy did not demonstrate height disparity as adults, compared to individuals without such a procedure or relative to their genetically determined height. Level of Evidence: 3.

Indexed as

attained heightheight disparitypolygenic risk scoretonsillectomy

Identifiers

PMID40909198
PMCPMC12406076

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.