ReviewFrontiers in cell and developmental biology2025
The secrets of menstrual blood: emerging frontiers from diagnostic tools to stem cell therapies.
Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Hydrogel-Based Systems in Intrauterine Adhesions: Bridging the Gap from Bench to Bedside.Advanced healthcare materials · 2026Review
- Protocol for isolation and characterization of small extracellular vesicles from human menstrual fluid using size-exclusion chromatography.STAR protocols · 2026Article
- Single-cell and spatial transcriptomics reveal Thbs1-CD36 crosstalk between Kupffer and hepatic stellate cells following mesenchymal stem cell-derived small extracellular vesicles transplantation, alleviating liver fibrosis.Journal of nanobiotechnology · 2026Article
- Interpretations of Menstrual Blood Appearance and Diagnostic Potential Among Social Media Users: Cross-Sectional Mixed Methods Social Media Listening Study.Journal of medical Internet research · 2026Article
- Menstrual Effluent in the Pathogenesis and Diagnosis of Endometriosis-A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Beyond waste: menstrual blood as a powerful diagnostic tool for women's health.Annals of medicine and surgery (2012) · 2026Article
- Comparative analysis of the bio-safety of HuMSCs and HuMenSCs in the nude mice and their impacts on reproductive organs' histological morphology.Cell transplantationArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Menstrual blood (MB), a biofluid rich in diverse cell types and biomolecules, has emerged as a vital resource for investigating female reproductive health and diseases because of its unique composition and noninvasive accessibility. This review explores the potential of MB in medical research and clinical applications, focusing on its diagnostic and therapeutic prospects. For disease diagnosis, MB offers a noninvasive sampling method for identifying biomarkers in endometriosis, cervical cancer, and other gynecological conditions. Therapeutically, stem cells derived from MB (menstrual blood-derived stem cells, MenSCs) exhibit pluripotency, high proliferative capacity, and low immunogenicity, positioning them as promising candidates in regenerative medicine. Preclinical and clinical studies have demonstrated the efficacy of MenSCs in treating infertility, premature ovarian insufficiency, intrauterine adhesions, hepatic disorders, cutaneous injuries, and neurological diseases. MenSCs also exert therapeutic effects through paracrine mechanisms by releasing cytokines and exosomes that modulate immunity, attenuate inflammation, and promote tissue repair. Despite existing challenges, MenSCs hold substantial promise for developing novel therapeutic strategies across multiple disease domains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.