ArticleJournal of applied polymer science2025
A process optimization and release modeling of coaxial electrospun aligned core-shell poly (ethylene oxide-poly(l-lactide-co-glycolide)) nanofibers encapsulating nerve growth factor.
Article in Journal of applied polymer science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Magnetically responsive electrospun fibers as programmable bioactive scaffolds: From formulation design to magnetically triggered therapy and regeneration.Bioactive materials · 2027Review
- Simulation and Response Surface Methodology for Predicting Mass Transfer in Coaxial Electrospun Core-Shell Fibers.Micromachines · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Recent advances in neural regeneration have demonstrated the importance of incorporating proteins into polymeric capsules to provide both topographical and biochemical cues to cells. Coaxial electrospinning has emerged as a versatile technique for embedding delicate bioactive agents within core-shell nanofibers, enabling controlled and sustained drug release. In this study, we employed a design-of-experiment approach to systematically investigate how controllable parameters in coaxial electrospinning influence the diameter and size distribution of aligned poly (ethylene oxide-poly(l-lactide-co-glycolide) nanofibers loaded with nerve growth factor (NGF). Employing a Box-Behnken Design, we identified the optimal parameter levels to minimize the response variables and conducted a regression analysis. The results indicated that optimal core-shell nanofibers, with a minimized fiber diameter of 323 nm and a fiber size distribution of 2.37%, were achieved by setting the inner flow rate to 0.33 mL h
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Registered trials
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