ArticleFrontiers in neuroscience2025
Unusual presentation of neurobrucellosis presenting with the features of parkinsonism: two case reports and a review of the literature.
Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Case Report: Neurological brucellosis with behavioral abnormalities: a case of Brucella encephalitis with mild cognitive impairment.Frontiers in medicine · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Brucellosis, a zoonotic disease caused by Objective: To describe two cases of neurobrucellosis presenting with Parkinsonism-like symptoms and psychiatric manifestations, highlighting the diagnostic challenges and therapeutic responses in a rare manifestation of this zoonotic infection. Design/methods: We report two male patients from Saudi Arabia, aged 75 and 26, diagnosed with neurobrucellosis based on high Results: Prolonged antibiotic therapy led to significant clinical improvement in both patients, with marked reduction in both neurological and psychiatric symptoms. Despite improvement, residual Parkinsonism-like symptoms persisted, necessitating extended therapy and long-term follow-up. Conclusion: These cases emphasize the importance of considering neurobrucellosis in patients from endemic regions with atypical neurological and psychiatric symptoms. Early diagnosis through serological and molecular testing, followed by prompt and prolonged antibiotic therapy, is crucial for favorable outcomes.
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