ArticleEuropean heart journal open2025
Native T1 adds independent value for cardiovascular risk assessment beyond global longitudinal strain in an all-comers real-world clinical patient population.
Article in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aims: Deformation imaging remains underused for cardiovascular risk assessment. As tissue characterization has now been recognized as an additional assessment tool, we sought to investigate the significance of native T1 and extracellular volume (ECV) in an unselected clinical routine population. Methods and results: The single-centre, prospective cardiovascular magnetic resonance (CMR) registry included patients referred for clinical CMR. Left ventricle global longitudinal strain (GLS) was evaluated in long-axis views. Native T1 and ECV were assessed on septal, basal, or midventricular short-axis positions. Follow-up was conducted for primary (all-cause mortality and heart failure hospitalization) and secondary (all-cause mortality, hospitalized angina, and myocardial infarction) endpoints. The final population consisted of Conclusion: Native T1 was found to be an independent risk predictor beyond GLS as well as common clinical risk factors. This may justify the use of non-contrast CMR protocols in selected patients if contrast application is contraindicated.
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