ReviewRSC advances2025
Plasmonic sensing in microfluidic paper-based analytical devices integrated with metal nanoparticles: a review.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Biophotonics point-of-care diagnostics in low-resource settings: a South African perspective.Journal of biomedical optics · 2026Review
- Microfluidic-assisted metal nanoparticle synthesis: emerging trends toward optical sensing applications.RSC advances · 2026Review
- Paper-Based Biosensors for Monitoring Binding, Blocking, and Surrogate Neutralizing Antibody Responses Against Viral Infections.Biosensors · 2026Review
- Microfluidic Paper-Based Devices at the Edge of Real Samples: Fabrication Limits, Hybrid Detection, and Perspectives.Micromachines · 2026Article
- Paper-Based Microfluidic Devices: A Powerful Strategy for Rapid Detection.Micromachines · 2025Review
- Nanodevice Approaches for Detecting Micro- and Nanoplastics in Complex Matrices.Nanomaterials (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal nanoparticles (MNPs) have emerged as vital components in nanotechnology due to their unique ability to concentrate light at the nanoscale. This property makes them especially valuable in biosensing applications, where high sensitivity is essential. At the same time, cellulose-based materials like paper offer an affordable, widely available, and versatile platform, making them ideal for the development of paper-based microfluidic analytical devices (μPADs). These devices are revolutionizing point-of-care testing and on-site detection due to their scalability, portability, and biocompatibility. The synergy between the three-dimensional versatility of paper and the optical prowess of MNPs, has given rise to cutting-edge nanodevices that satisfy the ASSURED criteria-affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to end-users. This review provides a comprehensive examination of both plasmonic and non-plasmonic roles of MNPs within μPADs. It explores various detection strategies enabled by MNP integration, including colorimetric, surface-enhanced Raman scattering (SERS), chemiluminescent (CL), electrochemical, and electrochemiluminescent (ECL) methods. For each technique, the basic principles, practical implementation, and analytical strengths and limitations are discussed in the context of paper-based sensing platforms. Special attention is given to SERS-based μPADs, which offer rapid, sensitive, and low-volume analysis, with growing potential due to advances in portable Raman instrumentation. By addressing both plasmonic and non-plasmonic functionalities of MNPs, this work aims to provide a comprehensive perspective on the future of nanoparticle-integrated μPADs in global healthcare and analytical science. Additionally, the review highlights the importance of paper-based device architectures in supporting the integration of MNPs, ultimately enabling next-generation diagnostic and sensing platforms for diverse applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.