Evidence map›Paper›PMID 40908972›Full record

ArticleOpen forum infectious diseases2025

Evaluating Blood Culture Parameters to Identify Patients at Low Risk of Infective Endocarditis Among Those With Bacteremia by Gram-positive Cocci.

Nicolas Fourré, Virgile Zimmermann, Nicoleta Ianculescu, Thomas Brahier, Zélie Dennebouy, André Teixeira-Antunes, Pierre Monney, Georgios Tzimas, Laurence Senn, Lars Niclauss and 3 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicolas FourréInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0009-0006-1660-9365
Virgile ZimmermannInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0009-0005-1812-0216
Nicoleta IanculescuDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Thomas BrahierInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Zélie DennebouyInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
André Teixeira-AntunesInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Pierre MonneyDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-3083-7333
Georgios TzimasDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-2810-8887
Laurence SennInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Lars NiclaussDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-4453-5202
Matthias KirschDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-9213-7578
Benoit GueryInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Matthaios Papadimitriou-OlivgerisInfectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-0565-5105

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Identifying patients at low risk for infective endocarditis (IE) among those with bacteremia by Gram-positive cocci is critical to optimize cardiac imaging use. The aim was to assess the diagnostic performance of blood culture parameters in identifying patients at low risk for IE. Methods: Adult patients with bacteremia due to Results: Among 2165 episodes of bacteremia, 1165 (54%) were due to Conclusions: Simple blood culture parameters may help identify patients at low risk for IE. However, the approach classifies most patients as high-risk and may have limited impact on reducing echocardiography use.

Indexed as

bacteremiaEnterococcus faecalisinfective endocarditisStaphylococcus aureusstreptococci

Identifiers

PMID40908972
PMCPMC12405998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.