Evidence map›Paper›PMID 40908954›Full record

ArticleFrontiers in aging neuroscience2025

Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).

Sarah Mendorf, Konstantin G Heimrich, Hannah M Mühlhammer, Tino Prell, Aline Schönenberg

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah MendorfDepartment of Geriatrics, University Hospital Jena, Jena, Germany.
Konstantin G HeimrichDepartment of Geriatrics, University Hospital Jena, Jena, Germany.
Hannah M MühlhammerDepartment of Neurology, University Hospital Jena, Jena, Germany.
Tino Prell *Department of Neurology, University Hospital Jena, Jena, Germany.
Aline Schönenberg *Department of Geriatrics, University Hospital Halle, Halle, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Previous longitudinal studies have identified numerous factors influencing quality of life (QoL) in people of older age (PoA). However, most of these studies focus on group-level trends and fail to consider individual QoL trajectories or age-specific patterns over time. Methods: We investigated longitudinal changes in QoL among community-dwelling older adults using five waves (2010-2019) of the Survey of Health, Aging and Retirement in Europe (easySHARE). Clinically relevant changes were defined via the minimal clinically important difference (MCID). We applied linear regression and linear mixed models (LMM) to explore predictors of QoL trajectories. Results: Descriptive analyses showed that 2481 PoA (19.7%) experienced stable QoL between waves, based on changes below the MCID threshold of 3.18 points. The remaining participants exhibited consistent improvements or declines, with 1,701 different longitudinal patterns of QoL identified across the five time points. These individual patterns were further examined using LMM. LMM showed that the random effect of ID had the strongest impact on QoL across the five waves, suggesting highly individual QoL patterns. The influence of age was less significant compared to ID and decreased significantly after the addition of covariates. Conclusion: Our findings underscore the importance of individual-level analyses in aging research. While QoL may appear stable at the group level, individual trajectories vary considerably. This has important implications for the use of QoL as a primary endpoint in clinical trials, particularly in geriatric populations. Notably, age alone did not significantly influence QoL over time.

Indexed as

age factorseasySHARElongitudinal studiesolder adultsquality of lifeSHARE

Identifiers

PMID40908954
PMCPMC12405344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.