Evidence map›Paper›PMID 40908788›Full record

ArticleJournal of cosmetic dermatology2025

The Effect of Treatment With Hyaluronic Acid Dermal Fillers on Skin Changes and Quality of Life in Oncology Patients.

Eden Bar, Eliya Shachar, Ofir Artzi, Lyri Adar, Omer Shani, Adi Diner, Lee Pantanowitz Mabjeesh, Ido Wolf, Tamar Safra

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eden BarDermatology Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Eliya ShacharGray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ofir ArtziDermatology Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Lyri AdarDivision of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Omer ShaniDivision of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Adi DinerDivision of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Lee Pantanowitz MabjeeshDivision of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Ido WolfGray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Tamar SafraGray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients treated with cancer therapies often experience changes in physical appearance, body image perception, and self-esteem, which influence their quality of life (QoL).

aimsTo assess the effect of treatment with hyaluronic acid (HA) dermal fillers on QoL, safety, and perceived skin changes of oncology patients.

methodsA single-center prospective study conducted between 2021 and 2023 among female oncology patients aged 30-70 years receiving active cancer treatment. All participants completed a questionnaire describing their demographics, disease history, and experience with aesthetic procedures, their intention to undergo aesthetic treatments, and a QoL questionnaire. A subset of participants received treatment with HA fillers. The effect of filler treatment on facial skin features, efficacy, and safety was evaluated by independent dermatologists and by the participants 8-12 weeks after the intervention.

resultsIn total, 127 women (median age 57.1 years) with breast (58.3%), gynecological (33.9%), and other cancer types (7.9%) entered the study. Most participants (84.0%) reported no previous treatment with dermal fillers. Thirty-one participants received a single treatment with HA dermal fillers concurrently with cancer treatment and an optional touch-up 4 weeks later. At follow-up, statistically significant improvements in overall aesthetic facial appearance and specific skin quality parameters were observed. Mean QoL significantly improved, with notable improvements in self-esteem, self-perception, and overall participant feeling. Adverse events were minimal. Thirteen participants (41.9%) experienced mild dermal events. One participant developed a grade 1 delayed inflammatory reaction 6 months postinjection.

conclusionsHA fillers have the potential to improve QoL and self-perception among oncology patients undergoing active cancer therapy.

Indexed as

Cosmetic TechniquesDermal FillersHyaluronic AcidNeoplasmsQuality of LifeSkin AgingAdultAgedBody ImageFaceFemaleHumansMiddle AgedProspective StudiesSelf ConceptSurveys and QuestionnairesDermal FillersHyaluronic Acidaesthetic treatmentcancer treatmentdermal fillersquality of life

Identifiers

PMID40908788
PMCPMC12411806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.