Evidence map›Paper›PMID 40908700›Full record

ReviewCurrent drug delivery2026

Novel Drug Delivery Systems Approved by USFDA from 2019 to 2023: A Comprehensive Review.

Anfal F Almazyad, Nazrul Haq, Ibrahim A Alsarra, Sultan Alshehri, Prawez Alam, Mohd Imran, Faiyaz Shakeel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anfal F AlmazyadJoint Program Council in Drug Regulatory Affairs, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Nazrul HaqDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ibrahim A AlsarraDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Sultan AlshehriDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.
Prawez AlamDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Mohd ImranDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, Saudi Arabia.
Faiyaz ShakeelDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, tremendous progress in the field of novel drug delivery systems (NDDS), which has prompted the creation of new strategies to enhance treatment results and patient compliance. The goal of this comprehensive review is to provide a summary of the NDDS that the US Food and Drug Administration (USFDA) has approved from 2019 to 2023. Various databases, including PubMed, Scopus, USFDA, and patent websites were utilized to gather relevant information. The selected NDDSs were categorized based on their delivery route, such as oral, injectable, transdermal, pulmonary, nasal, ocular, and implantable. For each delivery route, the review provides a detailed analysis of the approved NDDSs, including their mechanisms of action, advantages, limitations, and clinical applications. Additionally, the review discusses the challenges faced during the development and commercialization of these systems, as well as the prospects and potential areas of improvement. The findings of this comprehensive review demonstrate the remarkable progress made in the field of NDDSs, with the USFDA approving several innovative technologies in recent years. The approved NDDSs have shown promising results in enhancing drug stability, bioavailability, and controlled release, leading to improved therapeutic outcomes and patient convenience. In conclusion, this comprehensive review provides a valuable resource for researchers, healthcare professionals, and pharmaceutical industries, offering insights into the latest advancements in NDDSs approved by the US FDA. The knowledge gained from this review can guide future research endeavors, foster innovation, and contribute to developing more effective and patient-friendly NDDS strategies.

Indexed as

Drug ApprovalDrug Delivery SystemsAnimalsHumansUnited StatesUnited States Food and Drug AdministrationAntibody drug-conjugateblock copolymer micellesmarketed productsnovel drug delivery systemspatentsUSFDA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.