Evidence map›Paper›PMID 40908684›Full record

ReviewCurrent diabetes reviews2026

Feimin in Glucose Homeostasis: Mechanistic Insights, Population Heterogeneity, and Therapeutic Potential.

Sijun Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sijun YangHuangshi Key Laboratory of Birth Defects Prevention, Department of Laboratory Medicine, Huangshi Maternity and Children's Health Hospital, Affiliated Maternity and Children's Health Hospital of Hubei Polytechnic University, Huangshi, 435000, Hubei, People's Republic of China.ORCID 0000-0003-4358-4002

Funding

Huangshi Municipal Health Commission Key Projects WJ2024006Hubei University of Traditional Chinese Medicine-Huangshi Maternal and Child Health Hospital Joint Fund 2024ZXHSFY13National Natural Scientific Foundation of China 81873780
6 · The paper itself

Abstract

The recent discovery of feimin, a feeding-induced myokine modulating glucose homeostasis via the MERTK pathway, offers a novel therapeutic avenue for metabolic disorders. While other studies delineate its acute metabolic effects in Han Chinese populations, critical gaps remain in understanding its mechanistic interplay, population generalizability, and long-term impacts. This perspective synthesizes current evidence, highlights limitations in study design and translational applicability, and proposes integrative approaches, spanning multi-omics, global consortia, and interventional trials, to unravel feimin's role in metabolic regulation. By addressing these challenges, feimin may emerge as a biomarker or therapeutic target for diabetes and related syndromes.

Indexed as

Blood GlucoseGlucoseHomeostasisAnimalsBiomarkersHumansBiomarkersBlood GlucoseGlucosecytokinesdiabetesFeiminglucose homeostasismer proto-oncogene tyrosine kinasemyokine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.