Evidence map›Paper›PMID 40908319›Full record

ArticleAesthetic plastic surgery2025

Combination Therapy Involving Pulsed Dye and Fractional CO

Zhongliang Lang, Guangdi Yin, Qiusheng Zhang, Xiaohong Zhong, Tao Lin, Jing Lv, Qiang Wang, Liping Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhongliang Lang *Department of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China.
Guangdi Yin *Department of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China.
Qiusheng ZhangDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China.
Xiaohong ZhongDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China.
Tao LinDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China.
Jing LvDepartment of Stomatology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China. prs@ustc.edu.cn.
Qiang WangDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China. qiang_wang0102@ustc.edu.cn.
Liping ZhaoDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, P.R. China. zhlip16@163.com.

Funding

USTC Research Funds of the Double First-Class Initiative YD9110002043
6 · The paper itself

Abstract

backgroundHypertrophic scarring is a common pathological condition often associated with significant clinical symptoms. In pediatric patients, it can impair function and is difficult to treat due to the limited availability of effective treatment options.

objectiveTo investigate the efficacy of pulsed dye and fractional CO

methodsA retrospective cohort study and a self-controlled before-and-after method were used. Thirty-six patients with 41 sites of hypertrophic scars who visited our hospital between July 2022 and December 2023 were included, comprising 18 males and 18 females, aged 2-17 years. All patients underwent a combination of pulsed dye and fractional CO

resultsThe study revealed a notable decline in the total patient and observer scar scale scores (74.3±4.7 versus 23.6±2.9), with a P-value of less than 0.001 for each specific POSAS score item at the 12 months follow-up period in comparison to the baseline. The overall satisfaction rate was 98%, and no serious adverse reactions were observed during the follow-up period.

conclusionPulsed dye and fractional CO LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Cicatrix, HypertrophicLasers, DyeLasers, GasPhonophoresisTriamcinolone AcetonideAdolescentChildChild, PreschoolCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleRetrospective StudiesTreatment OutcomeTriamcinolone AcetonideChildrenHypertrophic scarLaserLaser-assisted drug delivery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.