Evidence map›Paper›PMID 40908096›Full record

ArticleThe American journal of clinical nutrition2025

Predicting total body water in infants aged 0.5-24 months and the implications for measuring breast milk intake: a secondary analysis of isotope dilution data.

Marieke Aj de Sévaux, Pernille Kæstel, Hinke Haisma, Teresa Hm da Costa, Adriana Vázquez-Vázquez, Tinku Thomas, Regien Biesma, Rebecca Kuriyan, Grace Munthali, Aly Diana and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Marieke Aj de SévauxGlobal Health Unit, Department of Health Sciences, University Medical Center Groningen, Groningen, The Netherlands; Population Research Centre, Faculty of Spatial Sciences, University of Groningen, Groningen, The Netherlands. Electronic address: m.a.j.de.sevaux@umcg.nl.
Pernille KæstelNutritional and Health-related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Hinke HaismaPopulation Research Centre, Faculty of Spatial Sciences, University of Groningen, Groningen, The Netherlands.
Teresa Hm da CostaNutrition Department, University of Brasilia, Brasilia-Federal District, Brazil.
Adriana Vázquez-VázquezPopulation Policy and Practice Department, University College London, Great Ormond Street Institute of Child Health, London, United Kingdom.
Tinku ThomasDepartment of Biostatistics, St John's Medical College, Bengaluru, India.
Regien BiesmaJulius Global Health, University Medical Center Utrecht, The Netherlands.
Rebecca KuriyanDivision of Nutrition, St. John's Research Institute, Bengaluru, India.
Grace MunthaliNational Institute for Scientific and Industrial Research (NISIR), Lusaka, Zambia.
Aly DianaDepartment of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Ina S SantosPostgraduate Program in Epidemiology, Faculty of Medicine, Federal University of Pelotas, Pelotas, Brazil.
Andrew P HillsSchool of Health Sciences, College of Health and Medicine, University of Tasmania, Tasmania, Australia.
V Pujitha WickramasingheDepartment of Paediatrics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Shabina AriffDepartment of Pediatric and Child Health, The Aga Khan University, Pakistan.
M Nishani LucasDepartment of Paediatrics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Caroline S CostaPostgraduate Program in Epidemiology, Faculty of Medicine, Federal University of Pelotas, Pelotas, Brazil.
Shane A NorrisSAMRC (South African Medical Research Council) Developmental Pathways for Health Research Unit, Department of Pediatrics, University of the Witwatersrand, Johannesburg, South Africa; School of Human Development and Health, University of Southampton, Southampton, United Kingdom.
Vandana JainDepartment of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Helen MulolDepartment of Paediatrics, University of Pretoria, Pretoria, South Africa; Research Centre for Maternal, Fetal, Newborn, and Child Health Care Strategies, University of Pretoria, Pretoria, South Africa; Maternal and Infant Health Care Strategies Unit, South African Medical Research Council, Pretoria, South Africa.
Ute FeuchtDepartment of Paediatrics, University of Pretoria, Pretoria, South Africa; Research Centre for Maternal, Fetal, Newborn, and Child Health Care Strategies, University of Pretoria, Pretoria, South Africa; Maternal and Infant Health Care Strategies Unit, South African Medical Research Council, Pretoria, South Africa.
Birna ThorisdottirFaculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland; Unit of Nutrition Research, Health Science Institute, University of Iceland, Reykjavik, Iceland.
Inga ThorsdottirFaculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland; Unit of Nutrition Research, Health Science Institute, University of Iceland, Reykjavik, Iceland; Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Peter Sw DaviesChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Cornelia U LoechlNutritional and Health-related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Jonathan Ck WellsPopulation Policy and Practice Department, University College London, Great Ormond Street Institute of Child Health, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal body water (TBW) is commonly used to derive estimates of body composition. The deuterium oxide dose-to-mother (DTM) technique for measuring breast milk intake requires an estimate of infant TBW. The DTM calculation employs a prediction equation for estimating infant TBW from body weight (TBW

objectivesThe objectives of this study were to assess the bias of TBW predicted by the equation used in DTM calculations (TBW

methodsWe conducted a secondary analysis of 3756 TBW

resultsTBW

conclusionsThe equation used in DTM calculations provides biased TBW estimates. This has implications for measuring breast milk intake and nonmilk water intake and our understanding of nutritional needs during the first 2 y of life.

Indexed as

Body WaterBreast FeedingMilk, HumanBody CompositionBody WeightChild, PreschoolDeuterium OxideDrinkingFemaleHumansIndicator Dilution TechniquesInfantInfant, NewbornMaleDeuterium Oxideanthropometrybody compositionbreast milk intakedeuteriumdoubly labeled waterinfantisotope dilutiontotal body water

Identifiers

PMID40908096
PMCPMC12489350

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.