Evidence map›Paper›PMID 40907886›Full record

ReviewJournal of the American Academy of Child and Adolescent Psychiatry2026

Review and Developmental Model: Early Childhood Emotion Regulation and Co-Regulation in Autism.

Jessie B Northrup, Heather J Nuske, Alison E Hipwell, Carla A Mazefsky

Abstract readReview
In one paragraph

Review in Journal of the American Academy of Child and Adolescent Psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The inner life of autism: a call to action.Frontiers in pediatrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessie B NorthrupUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: northrupjb@upmc.edu.
Heather J NuskeUniversity of Pennsylvania Perelman School of Medicine, Pittsburgh, Pennsylvania.
Alison E HipwellUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Carla A MazefskyUniversity of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Funding

Parent-Child Interaction and Emotion Regulation in Preschoolers with Autism Spectrum DisorderK23MH127420 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie B Northrup · 2022 to 2026
$873k
Reducing Challenging Behaviors In Children With Autism Through Digital HealthK01MH120509 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI NUSKE, HEATHER J · 2020 to 2024
$773k
NIMH NIH HHS K01 MH120509NIMH NIH HHS K23 MH127420
6 · The paper itself

Abstract

objectiveEmotion regulation (ER) and dysregulation (ED) have significant impacts on the mental health and quality of life of autistic individuals and their families, yet little is known about ER development in early childhood autism. This paper proposes a developmental model of disruptions to early ER development, emphasizing parent-child co-regulation, to guide future research and clinical care.

methodEmpirical research on ER, ED, and parent-child co-regulation in young autistic children (mean age <6 years) was summarized. Insights from theoretical and empirical work on typical ER development, with a focus on parent-child co-regulation, were integrated with autism research to propose a novel developmental model.

resultsResearch on ER and ED in young autistic children remains limited and lacks a developmental framework. Parent-child co-regulation is identified as a key mechanism in ER development, operating across micro (moment-by-moment) and macro (long-term) time scales. Autism-specific challenges, such as pervasive and idiosyncratic triggers, reduced emotional awareness, and ambiguous emotional communication, can disrupt parent-child co-regulation. These disruptions reduce opportunities for teaching and internalizing effective ER strategies and can lead parents and children to rely on "quick fix" strategies (eg, avoidance), ultimately hindering long-term ER development and negatively affecting mental health.

conclusionUnderstanding disruptions to ER development in autism within parent-child interactions offers a framework for research and clinical care. Developing autism-specific measurement tools and using longitudinal, ecological, and "measurement burst" designs will be critical to uncovering disrupted dyadic processes. Future research and clinical efforts must address the unique experiences and needs of autistic children and their families. PLAIN LANGUAGE SUMMARY: Difficulties managing big emotions affect many parts of life for children with autism and their families. This paper summarizes what is known-and what is not known-about how young children with autism manage emotions and how parents support them. The authors proposed a new framework for understanding how autism-specific challenges can disrupt parent-child emotional interactions, making it harder for families to build coping strategies. This framework can guide future research and clinical interventions.

Indexed as

Autistic DisorderChild DevelopmentEmotional RegulationParent-Child RelationsChildChild, PreschoolHumansModels, Psychologicalautismearly childhoodemotion regulationmental healthparent–child relations

Identifiers

PMID40907886
PMCPMC12927339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.