Evidence map›Paper›PMID 40907040›Full record

ArticleIEEE transactions on bio-medical engineering2026

Advancing Point-of-Care Still's Murmur Identification: Evaluating the Efficacy of ConvNets and Transformers Using the StethAid Multicenter Heart Sound Database.

Youness Arjoune, Ko-Tsung Hsu, Robert Geggel, Jospeh May, Ian Hovis, Tara Cosgrove, Robin W Doroshow, Raj Shekhar

Abstract readMulticenter Study
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Youness Arjoune
Ko-Tsung Hsu
Robert Geggel
Jospeh May
Ian Hovis
Tara Cosgrove
Robin W Doroshow
Raj Shekhar

Funding

Automated point-of-care identification of innocent Still's murmur in childrenR42HL131081 · NHLBI · AUSCULTECH DX, LLC · PI DOROSHOW, ROBIN, SHEKHAR, RAJ · 2019 to 2020
$1.5M
NHLBI NIH HHS R42 HL131081
6 · The paper itself

Abstract

backgroundPrimary care providers (PCPs) are not successful in accurately identifying Still's murmur with no available clinical tools to aid in the process. Existing deep learning (DL) methods primaryly focused on adult pathological murmurs or murmur detection, lacking dedicated approaches for Still's murmur. Furthermore, the absence of a specialized database hampers the development and validation of AI models for pediatric populations.

objectiveTo collect a pediatric dataset and evaluate DL methods in identifying Still's murmur in pediatric patients from phonocardiograms (PCGs) acquired using the StethAid digital auscultation platform.

methodsWe collected a large pediatric dataset (>2 hours of heart sound data) from four pediatric medical centers using StethAid, in addition to our previous Littmann 4100 dataset, which consisted of 1450 heart sound recordings. The StethAid dataset comprises 527 PCGs with diagnoses from four expert pediatric cardiologists. This dataset was used to train convolution- and pure attention-based models, which are our designed architecture SQ-NET, ResNet18, audio spectrogram transformer (AST), data-efficient transformer (DeiT), shifted windows (Swin) transformer, self-distillation with no labels (DINO). These methods were trained on segmented heart sounds except AST.

resultsDL methods achieved a sensitivity of 90.7%-100%, specificity of 75%-98.2%, and accuracy of 91.3%-98.5%. These results reflect post-hoc comparisons and highlight the potential of DL models to distinguish Still's murmur from other innocent and pathological murmurs. Pretraining on domain specific Littmann 4100 dataset improved models' performance by at least 2% over training from scratch.

conclusionBoth ConvNets and transformers enjoyed high performance in Still's murmur identification. SIGNIFICANCE: The proposed Still's murmur solution can assist PCPs in recognizing Still's murmur from other heart murmurs, potentially reducing unnecessary specialty referrals and the use of echocardiography. Additionally, StethAid could enhance PCPs' auscultation skills for Still's murmur by providing instant feedback, a feature often lacking in current clinical workflows.

Indexed as

Deep LearningHeart MurmursHeart SoundsPoint-of-Care SystemsSignal Processing, Computer-AssistedAdolescentChildChild, PreschoolDatabases, FactualFemaleHumansInfantInfant, NewbornMalePhonocardiography

Identifiers

PMID40907040
PMCPMC12705212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.