Evidence map›Paper›PMID 40907006›Full record

ArticleACS applied materials & interfaces2025

Multifunctional Hybrid Membrane-Coated Nanomotors for Magnetically Guided, Cascade-Activated Chemoimmunotherapy for Triple-Negative Breast Cancer.

Man Lung Lee, Li Wang, Jack Chun Hin Chen, Ellen Ngar-Yun Poon, Dinggeng He, Hung-Wing Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Man Lung LeeDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China.
Li WangCollege of Life Science, Hunan Normal University, Changsha 410081, China.
Jack Chun Hin ChenSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China.
Ellen Ngar-Yun PoonSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China.
Dinggeng HeCollege of Life Science, Hunan Normal University, Changsha 410081, China.ORCID 0000-0003-1481-6468
Hung-Wing LiDepartment of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China.ORCID 0000-0003-4840-1965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a multifunctional hybrid membrane-coated nanomotor for cancer chemoimmunotherapy, which consists of mesoporous silica-coated iron oxide nanoparticles (MF) as a drug carrier, loaded with doxorubicin (DOX), l-arginine (l-arg), and glucose oxidase (GOx), and camouflaged with a hybrid of red blood cell membranes (mRBC) and cancer cell membranes (CCM). RM-GDL-MF has a cascade of catalytic reactions, where glucose is catalyzed by GOx to produce H

Indexed as

ImmunotherapyTriple Negative Breast NeoplasmsAnimalsArginineCell Line, TumorDoxorubicinDrug CarriersErythrocyte MembraneFemaleGlucose OxidaseHumansMiceReactive Oxygen SpeciesSilicon DioxideArginineDoxorubicinDrug CarriersGlucose OxidaseReactive Oxygen SpeciesSilicon Dioxidecell membrane coatingchemotherapyimmunotherapynanomotortriple-negative breast cancer

Identifiers

PMID40907006
PMCPMC12447376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.