Evidence map›Paper›PMID 40906792›Full record

ArticlePloS one2025

Micronutrient dynamics and deficiency risk across pregnancy and postpartum in a Slovak cohort.

Alexandra Kristufkova, Neha Basheer, Katarina Koprdova, Matus Lieskovsky, Michal Fresser, Norbert Zilka

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Alexandra Kristufkova1st Department of Obstetrics and Gynecology, St. Cyril and Method's Hospital, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.
Neha BasheerInstitute of Neuroimmunology of Slovak Academy of Sciences, Bratislava, Slovak Republic.ORCID https://orcid.org/0000-0003-3669-3825
Katarina KoprdovaDepartment of Obstetrics and Gynecology, Bory - Penta Hospitals, Bratislava, Slovak Republic.
Matus LieskovskyMumo Health j. s. a., Bratislava, Slovak Republic.
Michal FresserMumo Health j. s. a., Bratislava, Slovak Republic.
Norbert ZilkaInstitute of Neuroimmunology of Slovak Academy of Sciences, Bratislava, Slovak Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the dynamics in blood concentrations of vitamins (A, B6, B12, D, E,), trace elements such as selenium, magnesium, zinc, and iron (transferrin), and metabolite homocysteine during pregnancy and postpartum.

designCross-sectional, national cohort study conducted between January and June 2024.

settingSlovakia. POPULATION: Pregnant and postpartum women.

methodsFrom venous blood and capillary dry blood spot micronutrients were analysed using standard biochemical and biophysical methods.

main outcome measuresGroup differences in blood micronutrient levels across pregnancy and postpartum.

resultsOur findings reveal significant differences in maternal micronutrient levels across pregnancy and postpartum. While some nutrients, including vitamin D and folate, remained relatively stable, others such as vitamin A, B12, iron and zinc were observed at lower levels, and vitamin E at higher levels during pregnancy. Vitamin E levels in the 3rd trimester frequently exceeded reference values for the general adult population, whereas zinc levels were significantly lower postpartum. We observed high prevalence of vitamin B12 and iron deficiencies, as indicated by transferrin saturation, particularly in the 3rd trimester. Vitamin D deficiency was prevalent throughout pregnancy and postpartum. Finally, our analysis demonstrated that dried blood spot (DBS) technology provides comparable results to venous blood analysis for measuring vitamin A, D and homocysteine levels.

Indexed as

MicronutrientsPostpartum PeriodPregnancy ComplicationsAdultCohort StudiesCross-Sectional StudiesFemaleHomocysteineHumansIronPregnancySlovakiaYoung AdultZincHomocysteineIronMicronutrientsZinc

Identifiers

PMID40906792
PMCPMC12410874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.