Evidence map›Paper›PMID 40906751›Full record

ArticlePloS one2025

Quantitative evaluation of therapeutic effect of silver needle thermal conduction therapy on myofascial trigger point.

Yue Qin, Yue Wang, Chunxin Wo, Zhenmin Wang, Zilong Yu, Yuanxin Huang, Lin Wang

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yue QinClinical Medicine College, Guizhou Medical University, Guiyang, Guizhou, China.ORCID https://orcid.org/0000-0002-3114-6243
Yue WangClinical Medicine College, Guizhou Medical University, Guiyang, Guizhou, China.
Chunxin WoClinical Medicine College, Guizhou Medical University, Guiyang, Guizhou, China.
Zhenmin WangDepartment of Imaging, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Zilong YuClinical Medicine College, Guizhou Medical University, Guiyang, Guizhou, China.
Yuanxin HuangDepartment of Algology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Lin WangDepartment of Algology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.ORCID https://orcid.org/0000-0001-5438-0932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn clinical practice, silver needle thermal conduction therapy has a definite effect on myofascial pain syndrome (MPS). However, there is a lack of objective evidence to evaluate the efficacy of this therapy. This study aimed to assess the effectiveness of silver needle thermal conduction therapy on MPS rats by objective therapeutic index.

methodsMPS model was established by blunt strick combined with centrifugal running training. MPS rats were divided into model and treatment groups, with a synchronized control group. The model group received no treatment, whereas the treatment group underwent silver needle thermal conduction therapy. The T2 value and stiffness values were evaluated by magnetic resonance imaging and sound touch elastography. The ultrastructure of muscle mitochondria was examined using transmission electron microscopy, and the Silent mating type information regulation 2 homolog 3 (SIRT3) expression level was evaluated by western blotting.

resultsT2 values and elastic modulus values in the treatment group were lower than those in the model group, and there was no difference between the treatment group and the control group. Mitochondrial damage was observed in the model group, and the degree of mitochondrial damage in the treatment group was less than that in the model group. SIRT3 expression in the treatment group was down-regulated compared with the normal group, but up-regulated compared with the model group.

conclusionThe silver needle thermal conduction therapy demonstrates the ability to reduce muscle inflammation and stiffness and facilitate the repair of damaged muscle mitochondria.

Indexed as

Acupuncture TherapyMyofascial Pain SyndromesSilverTrigger PointsAnimalsDisease Models, AnimalMagnetic Resonance ImagingMaleNeedlesRatsRats, Sprague-DawleySilver

Identifiers

PMID40906751
PMCPMC12410818

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.