ArticlePloS one2025
Application of Sterile Insect Technique (SIT) for Aedes albopictus (Skuse, 1895) in Sri Lanka: Dose optimization, mating competitiveness and release ratios.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundSri Lanka has experienced severe dengue epidemics in recent years, despite the extensive vector control measures taken. Therefore, it is necessary to find sustainable vector control strategies against dengue. Novel vector control tools need to be tested for the feasibility of applying them against local vectors. Sterile Insect Technique (SIT) is an increasingly popular vector control technique which has been adopted by many countries to suppress insect pest populations and is being tested for dengue vectors.
methodsIn this study, SIT was developed for Aedes albopictus (Skuse, 1895), one of the 2 dengue vectors present in Sri Lanka. The optimum radiation dose for sterilizing male pupae (age 24-48 hours) using a Co 60 source was determined based on the post-irradiation pupal and adult survival in males and induced sterility in females at different doses. Further, the effect of irradiation on mating competitiveness of the selected mosquito strain was assessed under laboratory and semi-field conditions. The optimum release ratio of irradiated males to wild males was assessed in laboratory and semi-field settings.
resultsThe optimum radiation dose was 50 Gy among the series of doses (25, 30, 40, 50, 60, and 70 Gy) tested. When pupae were exposed to the optimal radiation dose, 100% pupal survival, 19-day median adult survival time and 99% induced sterility resulted. A 5:1 ratio of irradiated males to non-irradiated laboratory-reared or wild males in laboratory cages resulted in induced sterility of 75% and 62%, respectively. The respective values were 74% and 61% in large semi-field cages. Fried Competitiveness Index (FCI) of irradiated males against wild males of laboratory and wild origin were 0.63 and 0.43 in laboratory cages and 0.57 and 0.55 in large semi-field cages.
conclusionThe males of Ae. albopictus irradiated at 50 Gy are adequately sterile and are competitive against the wild males. The release ratio of 5:1 irradiated males to wild males is a suitable ratio for the field application of SIT. The findings of the study will be important for the development of a protocol for future application of SIT for Ae. albopictus in Sri Lanka.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.