ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025
Incidence and Risk Factors for Progression of Acute Kidney Injury to Chronic Kidney Disease After Liver Transplantation: A Retrospective Cohort Study.
Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Reply: Chronic kidney disease after liver transplantation: Accurate measurement, early acute kidney injury, and renal-protective strategies.World journal of transplantation · 2026Article
- Rethinking chronic kidney disease risk after liver transplantation.World journal of transplantation · 2026Article
- Incidence and Risk Factors for Progression of Acute Kidney Injury to Chronic Kidney Disease After Liver Transplantation: A Retrospective Cohort Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
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Authors and funding
10 authors.
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Abstract
Acute kidney injury (AKI) following liver transplantation has the potential to progress to chronic kidney disease (CKD), which can result in extended hospital stays, elevated healthcare costs, and increased mortality rates. This retrospective cohort study seeks to examine the prognosis of AKI progression to CKD post-liver transplantation and to identify its independent risk factors. A cohort of 443 patients who developed AKI post-liver transplantation was analyzed, with participants categorized into a CKD group and a non-CKD group. The progression of AKI to CKD was observed in 29.3% (130 out of 443) of cases. Patients who developed CKD exhibited a significantly higher 1-year mortality rate of 4.6% (p = 0.004). Multivariate logistic regression analysis identified several independent risk factors for the progression from AKI to CKD, including preoperative diabetes (odds ratio [OR] 2.62; 95% confidence interval [CI] 1.32, 5.21), hepatic malignancy (OR 1.95; 95% CI 1.06, 3.57), elevated preoperative serum creatinine (SCr) levels (OR 1.02; 95% CI 1.01, 1.03), transition from postoperative AKI to acute kidney disease (AKD) (OR 3.99; 95% CI 1.94, 8.23), AKD stages 2 and 3 (OR 2.48; 95% CI 1.33, 4.61), and an estimated glomerular filtration rate (eGFR) of less than 60 mL/min/1.73 m
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