Evidence map›Paper›PMID 40906409›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Partial Deletion of the Carboxyl-Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum-Associated Degradation.

Miryeong Yoo, Sungeun Lee, Jieun Kim, Sunyeong Cha, Min Young Lee, Yeon Jeong Hwang, Woo-Ri Ko, Taeeun Kim, A-Ran Kim, Trang H T Trinh and 3 more

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Partial Deletion of the Carboxyl-Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum-Associated Degradation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Miryeong YooDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.ORCID https://orcid.org/0009-0001-0949-1593
Sungeun LeeDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.
Jieun KimDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.
Sunyeong ChaDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.
Min Young LeeDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.
Yeon Jeong HwangDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.
Woo-Ri KoDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.
Taeeun KimDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.
A-Ran KimDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.
Trang H T TrinhDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.
Young-Mi KimDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.
Yong-Pil CheonDivision of Developmental Biology and Physiology, Department of Biotechnology, Institute for Basic Sciences, Sungshin University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-8497-9257
Chongsuk RyouDepartment of Pharmacy, College of Pharmacy, and Institute of Pharmaceutical Science & Technology, Hanyang University ERICA, Ansan, Republic of Korea.ORCID https://orcid.org/0000-0001-8363-1059

Funding

Korea Health Industry Development Institute HI16C1085National Research Foundation of Korea (NRF) 2020R1A6A1A03042854National Research Foundation of Korea (NRF) 2020R1F1A1074328
6 · The paper itself

Abstract

Cellular prion protein (PrP

Indexed as

Endoplasmic ReticulumEndoplasmic Reticulum-Associated DegradationPrion ProteinsProtein Sorting SignalsPrPC ProteinsAnimalsArvicolinaeCell LineEndoplasmic Reticulum Chaperone BiPGene Knock-In TechniquesMiceMice, TransgenicPrion DiseasesEndoplasmic Reticulum Chaperone BiPHspa5 protein, mousePrion ProteinsProtein Sorting SignalsPrPC Proteinsendoplasmic reticulum–associated degradationgene expression regulationGPI‐linked proteinsprion proteinsunfolded protein response

Identifiers

PMID40906409
PMCPMC12410294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.