Evidence map›Paper›PMID 40906293›Full record

ReviewArchives of microbiology2025

Creating a designer cyanobacterial ecosystem for the sustainable production of biomass rich in sun-protecting compounds: mycosporine-like amino acids and scytonemin.

Bhavya Pandey, Abhijeet Sharma, Shanthy Sundaram, Adi Nath

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bhavya PandeyDepartment of Botany, Central Instrumentation Facility, Nehru Gram Bharati Deemed to University, Prayagraj, 221505, India.
Abhijeet SharmaCentre of Biotechnology, University of Allahabad, Prayagraj, 211006, India.
Shanthy SundaramCentre of Biotechnology, University of Allahabad, Prayagraj, 211006, India.
Adi NathDepartment of Botany, Central Instrumentation Facility, Nehru Gram Bharati Deemed to University, Prayagraj, 221505, India. adinathupadhyay@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review study examines an innovative biotechnological strategy aimed at creating a specialized cyanobacterial ecosystem designed to produce high-quality biomass abundant in compounds that provide protection against solar radiation, specifically scytonemin and mycosporine-like amino acids (MAAs). The remarkable ability of cyanobacteria to produce biomass that is both sustainable and environmentally friendly has attracted considerable attention in recent years, largely due to its wide-ranging applications in various industries. However, a significant challenge remains: the concentrations of these beneficial metabolites within cyanobacteria are typically very low, rendering industrial-scale production economically unviable. To tackle this limitation, the field of synthetic biology offers a promising avenue for improvement. By utilizing advanced genetic and metabolic engineering techniques, strategically modification can be done in specific cyanobacterial strains to optimize their metabolic pathways. This optimization may lead to enhanced production efficiencies and elevated yields of UV-protective chemicals, which are vital for protecting the organisms from harmful ultraviolet radiation as well as for potential applications in sunscreens and UV-blocking materials. In addition to discussing these engineering strategies, this article delves into the intricate molecular mechanisms underlying UV protection in cyanobacteria. Understanding the role of specific metabolites in shielding these microorganisms from UV damage can provide insight into both the natural resilience of cyanobacteria and the potential for engineered strains to yield higher concentrations of these valuable compounds. Through a comprehensive exploration of these topics, we can better appreciate the dual promise of cyanobacteria: their potential as a sustainable biomass resource and their capabilities in mitigating environmental stressors through enhanced UV protection.

Indexed as

Amino AcidsCyanobacteriaIndolesPhenolsSunscreening AgentsBiomassEcosystemMetabolic EngineeringUltraviolet RaysAmino AcidsIndolesPhenolsscytoneminSunscreening AgentsCyanobacteriaMycosporin like amino acidsScytoneminSunscreensSynthetic ecologyUV stress

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.