Evidence map›Paper›PMID 40906248›Full record

ArticleHNO2025

[Volumetry of the olfactory bulb - One component in the objectification of disorders of the sense of smell].

Stefanie Keweloh, Jörg-Michael Nebel, Daniel Overhoff, Stephan Waldeck

Abstract readEnglish Abstract
In one paragraph

Article in HNO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefanie KewelohKlinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Bundeswehrzentralkrankenhaus Koblenz, Rübenacher Str. 170, 56072, Koblenz, Deutschland. stefaniekeweloh@bundeswehr.org.
Jörg-Michael NebelKlinik für Hals-Nasen-Ohrenheilkunde, Bundeswehrzentralkrankenhaus Koblenz, Koblenz, Deutschland.
Daniel OverhoffKlinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Bundeswehrzentralkrankenhaus Koblenz, Rübenacher Str. 170, 56072, Koblenz, Deutschland.
Stephan WaldeckKlinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Bundeswehrzentralkrankenhaus Koblenz, Rübenacher Str. 170, 56072, Koblenz, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disorders of olfaction are a frequent reason for an assessment in otorhinolaryngology. Particularly when the results of subjective and/or objective olfactometry are inconclusive, additional objective findings are required to verify disorders of the sense of smell. Based on practical experience and considering the current literature, this article is intended as an aid in the preparation of supplementary radiological reports. The importance of comprehensive up to date standard imaging including olfactory bulb volumetry in addition to a detailed medical history and, if applicable, previous findings should be emphasized. In addition to the documentation of alterations in the anatomical structures involved in olfaction, which support the reported disorders in the sense of smell, special neuroradiological examination sequences for the visualization of the olfactory bulb, including a volumetric measurement of the same, can provide an objective component for the assessment of sometimes only subjectively existing disorders of the sense of smell. In the majority of cases no valid comparative volumetry can be derived from a possibly pre-existing imaging study. Therefore, a comparison with olfactory bulb reference values, determined in studies for the presumed etiology and the extent of the disorder reported/determined by olfactometry is the only way to put the olfactory bulb volume in an almost objective relationship to the function of the sense of smell reported and/or determined by olfactometry.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingOlfaction DisordersOlfactory BulbTomography, X-Ray ComputedHumansOrgan SizeReproducibility of ResultsSensitivity and SpecificityMagnetic resonance imagingOlfactometryOlfactory bulbOlfactory dysfunctionRadiology

Identifiers

PMID40906248
PMCPMC12457542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.