ArticleEuropean radiology2026
Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Two-Pattern Imaging Features of Low-Grade Vascular Neoplasia of the Liver: Insights from a Two-Center Retrospective Study.Radiology. Imaging cancer · 2025Article
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13 authors.
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Abstract
objectivesThe aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL). MATERIALS AND
methodsIn this retrospective multicenter study, patients diagnosed with pathologically proven LGVNL between January 2014 and August 2024 and with cross-sectional imaging (CT or MRI) were included. Based on prior studies, we divided the patients into two groups: a group with typical LGVNL features and a group with atypical tumors. Univariable analysis and the logistic regression model were used to evaluate the outcome of typical and atypical LGVNL features.
resultsTwenty-eight patients were included (20 men, mean age 53.7 ± 13.4 [SD] years old). The median size of tumors at diagnosis was 22 mm [IQR, 10-80]. A typical LGVNL pattern including thick continuous peripheral arterial phase "flower petal shape" enhancement was found on MRI in 67% (18/27) with lobulated lesions (p = 0.001), a marked hypersignal on T2-weighted images (p = 0.003) and a high apparent diffusion coefficient (ADC) (mean tumor ADC, 2.1 × 10
conclusionThe typical imaging pattern of LGVNL that includes arterial phase "flower petal shape" enhancement with a marked hypersignal on T2-weighted images and a high ADC was seen in most cases. KEY POINTS: Question Low-grade vascular neoplasia of the liver, including hepatic small vessel neoplasms and anastomosing hemangioma, is a new entity of vascular tumors with few radiological descriptions. Findings Diagnostic imaging criteria include the "flower petal shape" enhancement pattern on arterial phase, a marked hypersignal on T2-weighted images and high ADC values. Clinical relevance This multicenter study provides clinical, pathological and imaging data on low-grade vascular neoplasia of the liver and highlights specific imaging features for its diagnosis. Knowledge of these imaging features helps eliminate differential diagnoses.
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