Evidence map›Paper›PMID 40906010›Full record

ArticleJournal of general internal medicine2026

Inhaled Cannabis, Asthma, and Chronic Obstructive Pulmonary Disease: A Population-Based Cross-Sectional Study of n = 379,049.

Alison S Rustagi, Abra M Jeffers, F Julian Graham, Beth E Cohen, Christopher G Slatore, Amy L Byers, Stanton A Glantz, Salomeh Keyhani

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cannabis Use and Risk of Chronic Rhinosinusitis and Sinus Surgery.Laryngoscope investigative otolaryngology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alison S RustagiCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA, USA. alison.rustagi@va.gov.ORCID 0000-0003-4880-7658
Abra M JeffersMongan Institute Health Policy Research Center, Massachusetts General Hospital, Boston, MA, USA.
F Julian GrahamCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA, USA.
Beth E CohenCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA, USA.
Christopher G SlatoreCenter to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, OR, USA.
Amy L ByersCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA, USA.
Stanton A GlantzRetired, Center for Tobacco Control Research & Education and Department of Medicine, University of California, San Francisco, CA, USA.
Salomeh KeyhaniCenter for Data to Discovery and Delivery Innovation (3DI), San Francisco VA Health Care System, San Francisco, CA, USA.

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Marijuana Use in Older Adults: Health, Function and Fall-Related InjuryR01AG058678 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI KEYHANI, SALOMEH · 2019 to 2023
$3.0M
Identifying older adults who benefit from lung cancer screeningR03AG082924 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI RUSTAGI, ALISON SILVIS · 2023 to 2024
$307k
CSRD VA IK2 CX002713CSRD VA IK6 CX002386NIA NIH HHS 1R03AG082924NIA NIH HHS 5R01AG058678NIA NIH HHS P30 AG044281NIA NIH HHS R01 AG058678NIA NIH HHS R03 AG082924Simon Memorial Fund 7710-138339-7500274-45U.S. Department of Veterans Affairs CX002713VA VISN21 Early Career Award Program
6 · The paper itself

Abstract

backgroundCannabis may cause chronic pulmonary disease. Prior studies have been limited by low cannabis exposure, lack of data on tobacco cigarettes, and/or limited numbers of those without tobacco cigarette use.

objectiveTo examine whether inhaled cannabis associated with asthma and chronic obstructive pulmonary disease, independent of tobacco cigarettes.

designCross-sectional analysis of population-based, nationally representative survey data.

participantsAdults 18-74 years who participated in the 2016-2020 Behavioral Risk Factor Surveillance System surveys. MAIN MEASURES: The exposure was past-30-day cannabis use, from 0 (0/30 days) to 1 (30/30 days). Outcomes were self-reported diagnoses by a medical professional of asthma or chronic obstructive pulmonary disease. We used multivariable logistic regression to test whether inhaled cannabis was associated with odds of disease, adjusted for sociodemographics and tobacco cigarette use (current/former/never). Pre-specified analyses restricted to those with no lifetime tobacco cigarette use. KEY

resultsAmong n = 379,049, n = 23,035 reported inhaled cannabis use. Inhaled cannabis was associated with asthma overall (adjusted odds ratio (aOR) 1.44, 95% CI 1.26-1.63 for daily use) and among n = 221,767 with no lifetime tobacco cigarette use (aOR 1.51 for daily use, 95% CI 1.18-1.93). Inhaled cannabis was associated with chronic obstructive pulmonary disease overall (aOR 1.27 for daily use, 95% CI 1.10-1.46), with a non-significant elevated odds of disease among those with no lifetime tobacco cigarette use (aOR 1.54 for daily use, 95% CI 0.92-2.57).

conclusionsInhaled cannabis was associated with asthma and chronic obstructive pulmonary disease after adjusting for tobacco cigarette use. Among those with no lifetime tobacco cigarette use, the association with asthma persisted. Cannabis may be a potential modifiable risk factor for asthma and chronic obstructive pulmonary disease.

Indexed as

AsthmaCannabisMarijuana SmokingPopulation SurveillancePulmonary Disease, Chronic ObstructiveAdministration, InhalationAdolescentAdultAgedBehavioral Risk Factor Surveillance SystemCross-Sectional StudiesFemaleHumansMaleMiddle AgedUnited StatesasthmacannabisCOPDmarijuana

Identifiers

PMID40906010
PMCPMC12681257

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.