Evidence map›Paper›PMID 40905703›Full record

ArticleMicrobiology spectrum2025

Discovery of diverse anellovirus sequences in Thai human sequencing data.

Worakorn Phumiphanjarphak, Jinjutha Parkbhorn, Chumpol Ngamphiw, Sissades Tongsima, Pakorn Aiewsakun

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Worakorn PhumiphanjarphakDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-8879-5228
Jinjutha ParkbhornPornchai Matangkasombut Center for Microbial Genomics, Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Chumpol NgamphiwNational Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand.
Sissades TongsimaNational Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand.
Pakorn AiewsakunDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-5665-4041

Funding

Mahidol University MU-SRF-WC-02B/66National Science and Technology Development Agency JRA-CO-2563-12568-TH
6 · The paper itself

Abstract

Anelloviruses are part of the normal human viral flora. Although their diversity in humans has been investigated in many countries, and despite their initial detection in Thailand in 1999, knowledge of Thai anelloviruses remains very limited. This study analyzed 1,175 whole-genome sequencing data sets from Thai individuals to mine for potential anellovirus sequences. Our analyses detected anellovirus sequences in 149 data sets (12.68%), uncovering 434 partial anellovirus sequences and 77 complete genome sequences, characterized by the presence of terminal redundancy, complete IMPORTANCE: Anelloviruses are widespread in humans, yet their diversity remains poorly characterized in many regions, including Thailand. Here, we demonstrate that human sequencing data sets, originally generated without the intention for virome research, can be effectively mined for anellovirus sequences, including complete genomes. Our findings reveal a substantial number of previously unreported anelloviruses in Thailand, significantly expanding the known diversity of the virus. We also highlight potential limitations of the current anellovirus species classification scheme, which is based on pairwise

Indexed as

AnelloviridaeGenetic VariationGenome, ViralHumansOpen Reading FramesPhylogenySoutheast Asian PeopleThailandWhole Genome SequencingAnelloviridaeanellovirusviromevirus discovery

Identifiers

PMID40905703
PMCPMC12502646

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.