Evidence map›Paper›PMID 40905702›Full record

ArticlemBio2025

Phenotypic heterogeneity of capsule production across opportunistic pathogens.

Amandine Nucci, Julie Le Bris, Sara Diaz-Diaz, Lilibeth Torres-Elizalde, Eduardo P C Rocha, Olaya Rendueles

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amandine Nucci *Institut Pasteur, CNRS UMR3525, Microbial Evolutionary Genomics, Université Paris Cité, Paris, France.ORCID 0000-0001-7340-9075
Julie Le Bris *Institut Pasteur, CNRS UMR3525, Microbial Evolutionary Genomics, Université Paris Cité, Paris, France.ORCID 0009-0003-5500-0657
Sara Diaz-Diaz *Laboratoire de Microbiologie et Génétique Moléculaires (LMGM), CNRS UMR5100, Centre de Biologie Intégrative (CBI), CNRS, Université de Toulouse, Toulouse, France.ORCID 0000-0002-4864-1558
Lilibeth Torres-ElizaldeLaboratoire de Microbiologie et Génétique Moléculaires (LMGM), CNRS UMR5100, Centre de Biologie Intégrative (CBI), CNRS, Université de Toulouse, Toulouse, France.
Eduardo P C RochaInstitut Pasteur, CNRS UMR3525, Microbial Evolutionary Genomics, Université Paris Cité, Paris, France.ORCID 0000-0001-7704-822X
Olaya RenduelesInstitut Pasteur, CNRS UMR3525, Microbial Evolutionary Genomics, Université Paris Cité, Paris, France.ORCID 0000-0002-6648-1594

Funding

Agence Nationale de la Recherche ANR 22 CE20 00181,ANR-24-CHBS-0006
6 · The paper itself

Abstract

Phenotypic heterogeneity allows bacteria to adapt fast to changing environments. Extracellular capsules are well-known virulence factors, but also increase the cell adaptability and prevalence under hostile conditions. To limit their cost, some species regulate capsule production by genetic phase variation. Here, we demonstrated that phenotypic heterogeneity is a major mechanism controlling capsule production in

Indexed as

AcinetobacterBacterial CapsulesKlebsiellaKlebsiella pneumoniaeGene Transfer, HorizontalHumansPhenotypeVirulenceVirulence FactorsVirulence Factorscommensalismepigeneticshost-pathogen interactionsphage resistancevirulence

Identifiers

PMID40905702
PMCPMC12505892

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.