Evidence map›Paper›PMID 40905698›Full record

ArticlemSystems2025

Calprotectin protects

Wei H Lee, Amanda G Oglesby, Elizabeth M Nolan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Metal-independent effects of calprotectin on cocultures ofbioRxiv : the preprint server for biology · 2026
    Article
  4. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Wei H LeeDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0002-3062-0564
Amanda G OglesbyDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA.ORCID 0000-0003-4440-3840
Elizabeth M NolanDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0002-6153-8803

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NILES, JACQUIN C · 1985 to 2020
$25.6M
Metallobiochemistry of innate immunity and bacterial physiologyR01GM126376 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M, OGLESBY, AMANDA GAIL · 2017 to 2024
$2.4M
A*STAR National Science ScholarshipNIEHS NIH HHS P30 ES002109NIGMS NIH HHS R01 GM126376NIH HHS R01 GM126376
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsLeukocyte L1 Antigen ComplexPseudomonas aeruginosaQuorum SensingStaphylococcus aureusCoculture TechniquesGene Expression Regulation, BacterialHumansAnti-Bacterial AgentsLeukocyte L1 Antigen Complexcalprotectincoculturegene expressionmetal availabilityPseudomonas aeruginosaStaphylococcus aureus

Identifiers

PMID40905698
PMCPMC12455946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.