Evidence map›Paper›PMID 40905665›Full record

ArticleApplied and environmental microbiology2025

Mechanistic insights into the dimethylsulfoniopropionate synthesis enzyme BurB.

Nan Zhang, Yue Lin, Ning Wang, Hai-Yan Cao, Buke Zhang, Ya-Nan Gao, Yu-Zhong Zhang, Chun-Yang Li

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nan ZhangSchool of Bioengineering, State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Yue LinMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Ning WangMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Hai-Yan CaoMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Buke ZhangMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Ya-Nan GaoMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.
Yu-Zhong ZhangMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.ORCID 0000-0002-2017-1005
Chun-Yang LiMOE Key Laboratory of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China, Qingdao, China.ORCID 0000-0002-1151-4897

Funding

National Key Research and Development Program of China 2021YFA0909600National Natural Science Foundation of China 32200018National Natural Science Foundation of China 32330001National Natural Science Foundation of China 42276102National Natural Science Foundation of China 42306258National Natural Science Foundation of China W2441012Natural Science Foundation of Shandong Province ZR2024YQ076Taishan Scholars Program of Shandong Province tspd20240806Taishan Scholars Program of Shandong Province tsqn202306092
6 · The paper itself

Abstract

Dimethylsulfoniopropionate (DMSP) is one of the most abundant organosulfur molecules on Earth. It possesses various physiological functions in microorganisms and plays key roles in the global climate regulation. BurB, a SET (Suppressor of variegation, Enhancer of zeste and Trithorax) domain-containing enzyme identified from IMPORTANCE: The organosulfur compound dimethylsulfoniopropionate (DMSP) is an important participant in the global sulfur cycling. DMSP possesses various physiological functions in microorganisms and is also the main precursor of the "climate cooling" gas dimethyl sulfide (DMS). However, studies on the catalytic mechanisms of DMSP synthesis enzymes are limited. BurB, a specific

Indexed as

Bacterial ProteinsBurkholderiaMethyltransferasesSulfonium CompoundsCrystallography, X-RayMethionineS-AdenosylmethionineBacterial ProteinsdimethylpropiothetinMethionineMethyltransferasesS-AdenosylmethionineSulfonium Compoundscatalytic mechanismDMSP synthesisglobal sulfur cycleSET domainS-methyltransferase

Identifiers

PMID40905665
PMCPMC12542666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.