ArticleInternational journal of cosmetic science2026
Bioretinoids from microalgae: Boosting retinol performance and tolerability.
Article in International journal of cosmetic science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Bioretinoids from microalgae: Boosting retinol performance and tolerability.International journal of cosmetic science · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSkin ageing, hyperpigmentation, and texture are common dermatological concerns. Retinoids, including retinol, are widely used for their efficacy in treating these conditions. However, their side effects, such as irritation, often limit their use. Bakuchiol, a plant-derived retinoid alternative, has gained attention for its gentler profile, but its efficacy remains a subject of comparison with traditional retinoids. The aim of the present study was to evaluate the efficacy of a novel microalgae-derived bioretinoid (MBR) in comparison to retinol and bakuchiol in promoting skin regeneration, reducing ageing signs, and addressing hyperpigmentation.
methodsThe effects of MBR were evaluated in vitro for cell proliferation, melanin production, and extracellular matrix modulation. Clinically, MBR was applied to assess improvements in skin texture, firmness, elasticity, and pigmentation compared with reference treatments.
resultsIn vitro, MBR significantly outperformed both retinol and bakuchiol in cell proliferation, melanin reduction, and ECM modulation. In vivo, MBR improved skin texture, firmness, and pigmentation, showing results comparable to retinol. MBR also synergistically enhanced retinol's effects, improving hydration and reducing irritation.
conclusionMBR is a promising alternative to traditional retinoids, offering enhanced efficacy in skin regeneration and pigmentation control with a more favourable safety profile, especially when combined with retinol.
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