Evidence map›Paper›PMID 40905389›Full record

ArticleMycoses2025

New Asthma Diagnosis Codes or Short-Acting β

Ian Hennessee, Kaitlin Benedict, Dallas J Smith, Nicolas Barros

Abstract read
In one paragraph

Article in Mycoses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ian HennesseeCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Kaitlin BenedictCenters for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-0458-2493
Dallas J SmithCenters for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-5707-528X
Nicolas BarrosDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundAlthough several fungal infections have been linked to asthma development, the relationship between histoplasmosis and asthma development has not been fully described.

objectivesTo assess the incidence of new asthma diagnosis codes or short-acting β

methodsWe used a large health insurance claims database to identify patients with histoplasmosis with and without an asthma diagnosis code or a short-acting β

resultsAmong 1819 patients diagnosed with histoplasmosis, 252 (13.9%) received a new asthma diagnosis or SABA prescription in the subsequent year, more than double the proportion in the general population (5.8%). Pulmonary histoplasmosis and symptoms such as dyspnea and wheezing were associated with asthma diagnosis or SABA receipt.

conclusionThese findings suggest that histoplasmosis may predispose certain patients to airway hyperreactivity, particularly those with acute pulmonary symptoms. Further research is needed to elucidate potential mechanisms underlying these findings, which could inform strategies to mitigate post-infectious airway disease in affected patients.

Indexed as

Adrenergic beta-2 Receptor AgonistsAsthmaHistoplasmosisAdolescentAdultAgedDatabases, FactualDrug PrescriptionsFemaleHumansIncidenceInsurance, HealthMaleMiddle AgedUnited StatesYoung AdultAdrenergic beta-2 Receptor Agonistsasthmahealth insurancehistoplasmosisUnited States

Identifiers

PMID40905389
PMCPMC12666392

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.