ArticleJournal of feline medicine and surgery2025
Sedative and echocardiographic effects of intranasal or intramuscular administration of dexmedetomidine in healthy cats.
Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Multispecies Systematic and Critical Review of Intranasal Administration in Veterinary Anaesthesia and Emergency Care: Promising Evidence and Overlooked Challenges.Veterinary medicine and science · 2026Pooled it
- Computed Tomographic Volumetric Analysis of the Nasal Cavities in Domestic Cats (Felis catus) and Anatomical Implications for Intranasal Drug Delivery.Anatomia, histologia, embryologia · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectivesThe aim of the present study was to evaluate the sedative and echocardiographic effects of dexmedetomidine (DEX) administered via intranasal (IN) and intramuscular (IM) routes in cats.MethodsThis randomised, blinded crossover study involved eight healthy adult cats. Cats were randomly allocated to receive DEX 10 μg/kg via either the IN or IM routes. Sedation, mechanical nociception and muscle relaxation were subjectively assessed and physiological variables recorded at baseline and at 5 min intervals for up to 40 mins after drug delivery. Echocardiography was performed 15 mins after delivery.ResultsIn both treatment groups, sedation assessment scores significantly increased compared with baseline values (
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Registered trials
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