Evidence map›Paper›PMID 40905106›Full record

ReviewSoft matter2025

A tutorial for mesoscale computer simulations of lipid membranes: tether pulling, tubulation and fluctuations.

Maitane Muñoz-Basagoiti, Felix Frey, Billie Meadowcroft, Miguel Amaral, Adam Prada, Anđela Šarić

Abstract readReview
In one paragraph

Review in Soft matter, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maitane Muñoz-BasagoitiInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0003-1483-1457
Felix FreyInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0001-8501-6017
Billie MeadowcroftInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0003-3441-1337
Miguel AmaralInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0001-5755-0001
Adam PradaInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0003-3601-1265
Anđela ŠarićInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. andela.saric@ista.ac.at.ORCID http://orcid.org/0000-0002-7854-2139

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid membranes and membrane deformations are a long-standing area of research in soft matter and biophysics. Computer simulations have complemented analytical and experimental approaches as one of the pillars in the field. However, setting up and using membrane simulations can come with barriers due to the multidisciplinary effort involved and the vast choice of existing simulations models. In this review, we introduce the non-expert reader to coarse-grained membrane simulations at the mesoscale. Firstly, we give a concise overview of the modelling approaches to study fluid membranes, together with guidance to more specialized references. Secondly, we provide a conceptual guide on how to develop mesoscale membrane simulations. Lastly, we construct a hands-on tutorial on how to apply mesoscale membrane simulations, by providing a pedagogical examination of membrane tether pulling, shape and mechanics of membrane tubes, and membrane fluctuations with three different membrane models, and discussing them in terms of their scope and how resource-intensive they are. To ease the reader's venture into the field, we provide a repository with ready-to-run tutorials.

Indexed as

Cell MembraneComputer SimulationLipid BilayersMembrane LipidsMolecular Dynamics SimulationLipid BilayersMembrane Lipids

Identifiers

PMID40905106
PMCPMC12409609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.