Evidence map›Paper›PMID 40904980›Full record

ArticleCureus2025

Functional Mobility and Fall Risk Assessment in Lower Limb Amputees: Insights From the Timed Up and Go Test.

João Santos-Faria, Flávio Ribeiro, Vitor Sousa, Joana Santos-Costa, João Branco

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

João Santos-FariaPhysical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Flávio RibeiroPhysical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Vitor SousaPhysical Medicine and Rehabilitation, Hospital Senhora da Oliveira, Guimarães, Guimarães, PRT.
Joana Santos-CostaPhysical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
João BrancoPhysical Medicine and Rehabilitation, Unidade Local de Saúde de Coimbra, Coimbra, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower limb amputation (LLA) significantly affects mobility and increases fall risk, particularly in individuals with higher-level amputations and lower functional capacity. Effective tools to assess fall risk are essential in rehabilitation.

objectiveThis study was conducted at the Department of Physical Medicine and Rehabilitation, Coimbra University Hospital (HUC), Coimbra, Portugal. This study aimed to evaluate the performance of the Timed Up and Go (TUG) test in individuals with unilateral LLA, compare TUG times by amputation level (transfemoral vs. transtibial) and functional level (K2 vs. K3), and determine the predictive value of TUG for fall risk.

methodsA retrospective observational study was conducted with 99 unilateral LLA patients using prostheses. Participants were assessed using the TUG test, and data on demographics, functional classification, and fall history were collected. Statistical comparisons and ROC curve analysis were performed to identify significant differences and the optimal TUG cutoff for fall risk prediction.

resultsTransfemoral amputees had significantly slower TUG times than transtibial amputees (17 vs. 12 seconds; p < 0.001). Similarly, K2 amputees in both groups had significantly longer TUG times compared to their K3 counterparts (TF: 30 seconds vs. 14 seconds; TT: 27 seconds vs. 12 seconds; p < 0.001). Individuals with a history of falls also had significantly higher TUG times (26 vs. 10 seconds; p < 0.001). A TUG threshold of 18 seconds demonstrated a sensitivity of 100% and specificity of 69% (AUC = 0.81) for fall prediction.

conclusionThe TUG test is a reliable and practical tool for assessing functional mobility and fall risk in individuals with unilateral LLA. Performance varies significantly with amputation level and functional classification, and a cutoff of 18 seconds effectively identifies individuals at increased risk of falling.

Indexed as

fall riskfunctional mobilitylower limb amputationprosthetic rehabilitationtimed up and go test

Identifiers

PMID40904980
PMCPMC12404822

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.