Evidence map›Paper›PMID 40904967›Full record

ArticleCureus2025

An Alternative and Efficient Topicalization Technique for the Difficult Airway: A Case Series.

Rachel H Seet, Jocelyn Ong, Avinash Gobindram, Jessica E Malanjum

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachel H SeetAnaesthesia and Surgical Intensive Care, Changi General Hospital, Singapore Health Services, Simei, SGP.
Jocelyn OngAnaesthesiology, Singapore General Hospital, Singapore Health Services, Outram, SGP.
Avinash GobindramAnaesthesia and Surgical Intensive Care, Changi General Hospital, Singapore Health Services, Simei, SGP.
Jessica E MalanjumAnaesthesia and Surgical Intensive Care, Changi General Hospital, Singapore Health Services, Simei, SGP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective airway topicalization is essential for awake tracheal fiberoptic intubation (ATI) in patients with a difficult airway. Traditional methods often result in inadequate anesthesia at the laryngeal inlet, leading to patient discomfort, procedural difficulty, and excessive local anesthetic (LA) use. This case series introduces a novel, resource-efficient topicalization technique using standard operating theatre equipment. It employs two custom assemblies: one targets LA precisely at the laryngeal inlet, while the second augments spray-as-you-go application with supplemental airflow to enhance LA dispersion, oxygenation, and secretion clearance. Currently, no existing device combines all of these functions into a single, integrated system. In four varied cases, including patients with obstructive airway pathology, cystic hygroma, and oropharyngeal tumors, this method enabled smooth, first-attempt ATI with minimal patient discomfort. This demonstrates a feasible, effective, and procedurally efficient technique. A custom device (Avi Airway) is under development at our institution to integrate these features into a streamlined system. Further studies are planned to assess its broader clinical utility.

Indexed as

airway managementdifficult airwayfiberoptic bronchoscopyintratracheal intubationnebulizers and vaporizersoxygen inhalation therapytopical airway anaesthesia

Identifiers

PMID40904967
PMCPMC12401667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.