ReviewCureus2025
Minimally Invasive Pancreatoduodenectomy Compared to Open Pancreatoduodenectomy in Patients With Pancreatic Cancer: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pancreatic ductal adenocarcinoma is one of the most lethal malignancies, with a five-year survival rate below 8%. For resectable cases, pancreatoduodenectomy remains the standard treatment. While the open approach has traditionally been the primary treatment, minimally invasive techniques are gaining popularity due to advancements in surgical technology. This review evaluates postoperative safety and long-term outcomes of minimally invasive pancreatoduodenectomy compared to open pancreatoduodenectomy in patients with pancreatic ductal adenocarcinoma. A comprehensive database search yielded 636 articles, of which 9 studies met our inclusion criteria and were retrieved for analysis. These comprised eight cohort studies and one randomized controlled trial, including a total of 13,159 participants. Findings suggest that minimally invasive pancreatoduodenectomy may offer benefits, such as reduced blood loss, shorter hospital stays, faster recovery, and comparable surgical outcomes, making it a promising alternative to open pancreatoduodenectomy. However, minimally invasive approaches are also associated with challenges such as longer operative times and increased technical complexity. Therefore, further research and structured surgical training are essential to optimize clinical outcomes and guide decision-making.
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