Evidence map›Paper›PMID 40904958›Full record

ArticleCureus2025

A Case of Recurrent Dermatofibrosarcoma Protuberans With Fibrosarcomatous Transformation.

Nadiim C Doyle, Lord Mvoula, Ali Raza, Raji Mohammed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadiim C DoyleSurgery, St. George's University School of Medicine, True Blue, GRD.
Lord MvoulaSurgery, Lincoln Medical and Mental Health Center, Bronx, USA.
Ali RazaSurgical Oncology, New York City Health and Hospitals Corporation (NYC HHC) Lincoln, Bronx, USA.
Raji MohammedPathology and Laboratory Medicine, New York City Health and Hospitals Corporation (NYC HHC) Lincoln, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma with a generally low risk for metastasis. Most individuals are diagnosed with this neoplasm in the third or fourth decade of life, with the growth usually being no larger than 5 cm in maximum diameter at the time of diagnosis. The majority of these patients are treated with wide local excision, with most experiencing no recurrence or metastasis. There are, however, cases of DFSP that are characterized by the presence of a high-grade fibrosarcomatous component, which represents a more ominous finding and exhibits a far more troubling course. To underscore the difference in the two presentations, we report a case of DFSP with fibrosarcomatous transformation in a 45-year-old man with two previous excisions. The size of the lesion, along with other characteristic findings, has been shown to worsen prognosis and increase risk of metastasis. Therefore, further research into the condition and therapeutic modalities to help patients is warranted.

Indexed as

col1a1-pdgfrβ fusion proteindermatofibrosarcoma protuberansdfspdfsp-fsfibrosarcomatous transformationhigh mitotic countoncogenic chromosomal translocationsoft tissue sarcoma

Identifiers

PMID40904958
PMCPMC12404216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.