ArticleHealth science reports2025
Assessment of rs1205 and rs1130864 Polymorphisms of C-Reactive Protein Gene (
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Assessment of rs1205 and rs1130864 Polymorphisms of C-Reactive Protein Gene (Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Immune thrombocytopenia (ITP) is a rare autoimmune disease of platelet destruction with an unclear mechanism of pathogenesis. A well-known mechanism is the phagocytosis of antibody-coated platelets by the reticuloendothelial system. C-reactive protein (CRP) is a factor in the serum of patients, facilitating this process. We aimed to investigate the relationship between rs1205 (+1846 C>T) and rs1130864 (+1444 G>A) polymorphisms, along with their impact on susceptibility, disease course, treatment outcomes, and laboratory findings in ITP. Methods: Genomic DNA was extracted from 92 participants (46 patients and 46 healthy controls). Both rs1205 and rs1130864 polymorphisms were genotyped by the tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR) procedure. Laboratory and clinical data were also recorded at the time of admission. Results: The serum CRP levels were significantly higher in nearly all (95.6%) of the patients compared to controls (9.88 ± 3.15 mg/L vs. 5.06 ± 1.07 mg/L, Conclusion: In conclusion, findings demonstrate significantly elevated serum CRP levels in nearly all ITP patients, suggesting an inflammatory process in this disease and the diagnostic value of CRP. Moreover, two specific
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.