Evidence map›Paper›PMID 40904828›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2025

Opposing Relations of Reward Positivity with Anhedonia and Threat Sensitivity: Implications for Differential Dimensional Diagnosis.

Colin B Bowyer, Pablo Ribes-Guardiola, Keanan J Joyner, Christopher J Patrick

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Colin B BowyerDepartment of Psychology, Florida State University.
Pablo Ribes-GuardiolaDepartments of Basic and Clinical Psychology, and Psychobiology, Universitat Jaume I.
Keanan J JoynerDepartment of Psychology, University of California, Berkeley.
Christopher J PatrickDepartment of Psychology, Florida State University.

Funding

Traumatic Stress Across the Lifespan: A Biopsychosocial Training ProgramT32MH018869 · NIMH · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CARLA KMETT DANIELSON, DEAN Gaines KILPATRICK · 1988 to 2026
$7.2M
Integrated Clinical Neuroscience Training for Translational ResearchT32MH093311 · NIMH · FLORIDA STATE UNIVERSITY · PI LISA A ECKEL, Pamela K. Keel · 2012 to 2026
$2.3M
Between versus Within-Subject Models of the Protective Effect of Substance-Free Reward on Alcohol, Nicotine, and Marijuana Use and ProblemsR36DA050049 · NIDA · FLORIDA STATE UNIVERSITY · PI JOYNER, KEANAN J · 2020 to 2021
$120k
NIDA NIH HHS R36 DA050049NIMH NIH HHS T32 MH018869NIMH NIH HHS T32 MH093311
6 · The paper itself

Abstract

Given the substantial symptom overlap between anxiety and depressive disorders, researchers have sought to develop approaches for better differentiating these subdimensions of internalizing psychopathology. Neurophysiological indices of biobehavioral processes specific to either subdimension may provide a means for doing so. Here, we report evidence for opposing associations of a well-established neural indicator of reward responsiveness - the reward positivity (RewP) - with trait indices of depressive and phobic fear pathology. We show that these relationships were strengthened when controlling for their shared variance via regression modeling. Additionally, structural equation modeling revealed that broad negative affectivity (NA) constituted the shared variance between the two trait indices. Our findings point to the potential use of reduced RewP to improve differential diagnosis of depressive versus phobic fear conditions. They also indicate that variance shared between conditions of these types may operate to obscure their observed associations with neural indicators of core processes unique to each.

Indexed as

AnhedoniaDepressionFear DisordersNegative AffectivityReward PositivityReward ResponsivenessThreat Sensitivity

Identifiers

PMID40904828
PMCPMC12404276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.