ArticleBritish paramedic journal2025
Investigating pre-hospital troponin testing in the diagnosis of acute myocardial infarction: a systematic review.
Article in British paramedic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chest pain is one of the most common conditions presenting to emergency departments (EDs), with over 1.3 million attendances according to 2022/2023 UK data. The diagnosis of a myocardial infarction (MI) in pre-hospital settings is challenging, relying on careful history taking and electrocardiograms. Patients with ST elevation are transferred to hospitals with primary percutaneous coronary intervention (PPCI) facilities, whereas those without ST elevation are taken to local EDs for further work-up, including troponin testing. Point-of-care (POC) troponin tests are now available in the field, presenting the potential to diagnose MI in patients without ST elevation. This systematic review aims to investigate and determine whether POC troponin devices are effective in detecting patients with acute MI in the pre-hospital setting. Methods: This systematic review was performed in accordance with the PRISMA guidelines. A comprehensive search of the literature was created using the following databases: CINAHL, MEDLINE, EMBASE and DISCOVERY. Basic and advanced search strategies were used to identify papers using POC troponin testing in patients presenting in the pre-hospital setting with chest pain. Results: A total of five articles were identified demonstrating that a variety of pre-hospital POC troponin testing devices can detect MI in patients presenting with chest pain. One limitation of POC testing was that some patients with negative troponin results in the pre-hospital setting were confirmed to have MI in the hospital setting. Conclusion: Using POC troponin raises the possibility of detecting an MI, but cannot definitively exclude an MI. Further research is required to investigate the reliability of POC troponin testing in cohorts without ST elevation in the pre-hospital environment, which may expedite transfer to specialised PPCI hospitals over a local ED. The outcome of further research has the potential to positively impact outcomes of patients suffering with MI and to yield financial benefits via faster, more effective treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.