Evidence map›Paper›PMID 40904689›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2025

Effect of Intraocular Pressure Lowering Treatment on Peripapillary and Macular Vessel Density on Normotensive Eyes with Optic Disc Drusen: A Randomized Controlled Trial.

Ricardo Y Abe, Henrique F Pucci, Laura Oltramari, Luciana de Sá Quirino Makarczyk, Natanael A Sousa

Abstract read
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ricardo Y AbeOphthalmology, Hospital Oftalmológico de Brasília, Brasília, Brazil.ORCID https://orcid.org/0000-0002-7023-2144
Henrique F PucciOphthalmology, Hospital Oftalmológico de Brasília, Brasília, Brazil.
Laura OltramariOphthalmology, Hospital Oftalmológico de Brasília, Brasília, Brazil.
Luciana de Sá Quirino MakarczykOphthalmology, Hospital Oftalmológico de Brasília, Brasília, Brazil.
Natanael A SousaOphthalmology, Hospital Oftalmológico de Brasília, Brasília, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effect of intraocular pressure (IOP) reduction on peripapillary and macular vessel density parameters from optical coherence tomography angiography (OCT-A) in normotensive eyes with optic disc drusen (ODD). Randomized controlled trial, with 6 months of follow-up, including normotensive eyes with ODD divided into two groups: control group (lubricating eye drop) and case group (latanoprost 50mcg/ml). We used OCT-A to evaluate peripapillary and macular vessel density parameters. Data were collected at baseline and at 1, 3, and 6 months following the use of eye drops. This study included a total of 32 eyes (16 cases and 16 controls) from 19 patients. After 6 months, the group using latanoprost IOP reduced IOP to 10.8 ± 0.64 versus 13.5 ± 0.54 mmHg in the control group (

Indexed as

intraocular pressureoptical coherence tomographyOptic disc drusenoptic nervevessel density

Identifiers

PMID40904689
PMCPMC12404356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.