Evidence map›Paper›PMID 40904447›Full record

ArticleJournal of general and family medicine2025

A case of idiosyncratic drug-induced agranulocytosis because of sulbactam/ampicillin.

Kazuya Toda, Kaku Kuroda, Moe Kuroda, Kota Kawai, Yukihiro Sato

Abstract read
In one paragraph

Article in Journal of general and family medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kazuya TodaKamiichi Community Medical Support Unit Toyama University Toyama Japan.ORCID https://orcid.org/0009-0007-3210-8023
Kaku KurodaDivision of Geriatrics & Aging, Department of Medicine University of Rochester Rochester New York USA.ORCID https://orcid.org/0000-0001-6134-5465
Moe KurodaDepartment of General Medicine Toyama University Hospital Toyama Japan.ORCID https://orcid.org/0000-0001-8603-6562
Kota KawaiKamiichi Community Medical Support Unit Toyama University Toyama Japan.
Yukihiro SatoDepartment of Internal Medicine Kamiichi General Hospital Toyama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiosyncratic drug-induced agranulocytosis is a rare but life-threatening condition that requires immediate medical intervention. Although sulbactam/ampicillin (SBT/ABPC) is a widely used antibiotic, no prior case reports of its associated agranulocytosis were identified in our narrative literature review. We present a case of an 85-year-old man who developed agranulocytosis following SBT/ABPC treatment for pressure ulcer infection and aspiration pneumonia, accompanied by a narrative literature review. Awareness of this condition, prompt discontinuation of the suspected agent, and close monitoring of total white blood cell counts are essential for early detection and management of this life-threatening complication.

Indexed as

adverse effectagranulocytosisdrug‐inducedsulbactam/ampicillin

Identifiers

PMID40904447
PMCPMC12404175

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.