ReviewFrontiers in medicine2025
The impact of cataract surgery on tear film physiology: signs and symptoms, progression and treatment.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Tear Film Changes Following Anterior Segment Surgery: A Comprehensive Review of Pathophysiology, Clinical Features, and Recovery Time Course.Life (Basel, Switzerland) · 2026Review
- Association between systemic immune-inflammation index and postoperative optical quality in the early recovery phase after cataract surgery: a retrospective study.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to revise data published in the literature on the effects of cataract surgery on tear film characteristics, in relation to personal clinical surgical experience. Methods: A search was undertaken using PubMed (all years). Search terms included 'cataract surgery', 'phacoemulsification', 'cataract extraction', and 'manual small-incision cataract surgery', combined at first with 'ocular surface' and 'lacrimal film'. Second, we combined terms as 'cataract surgery', 'phacoemulsification', 'cataract extraction', 'manual small-incision cataract surgery' with 'dry eye disease (DED)' and 'dry eye syndrome'. Third, we combined terms such as 'cataract surgery', 'phacoemulsification', 'cataract extraction', and 'manual small-incision cataract surgery' with 'conjunctival sensitivity' and 'sensitivity of the conjunctiva'. Finally, we combined terms as 'cataract surgery', 'phacoemulsification', 'cataract extraction', and 'manual small-incision cataract surgery' with 'epiphora' and 'excessive tear'. Relevant in-article references not returned in our searches were also considered. Results: We analyzed collected data regarding DED characteristics and management of this condition related to cataract surgery. The relationship between ocular surface signs and symptoms and cataract surgery appears to be strong; indeed, TBUT, Schirmer's test, and OSDI scores are abnormal as early as 2 weeks after cataract surgery; however, there is conflicting evidence concerning the duration of these alterations and the restoration of the preoperative conditions, generally within 6 months after surgery. An increased risk of DED after cataract surgery is associated with pre-existing MGD. The chosen surgical procedure and pre- and postoperative pharmacological management are also key points in determining the extent of postoperative DED. Finally, no remarkable evidence was found regarding the association of "cataract surgery" with "hyperlacrimation" or "conjunctival sensitivity." Conclusion: The available evidence is discrepant regarding the onset, progression, and management of this condition. However, the association between cataract surgery and the occurrence of DED thereafter is well documented. Multicenter randomized trials are needed to strengthen the already published data, to investigate these divergencies, and to establish diagnostic-therapeutic protocols to manage this condition.
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