Evidence map›Paper›PMID 40904320›Full record

ReviewFuture cardiology2025

Supine hypertension and cardiovascular disease: controversies and advances.

Sally K Zimmermann, Kassem Farhat, Samir Zaman, Frances M Wang, Samir Y Hirpara, Raviv S Markovitz, Jiun-Ruey Hu, Paul A Beach, Stephen P Juraschek

Abstract readReview
In one paragraph

Review in Future cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sally K ZimmermannDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Kassem FarhatDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Samir ZamanDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Frances M WangDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Samir Y HirparaDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Raviv S MarkovitzDepartment of Medicine, Hackensack Meridian Health, Ocean University Medical Center, Brick, NJ, USA.
Jiun-Ruey HuDepartment of Cardiology, Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Paul A BeachDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Stephen P JuraschekDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

Prognostic Implications of Home-Based Blood Pressure Monitoring in Older AdultsR01HL158622 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2021 to 2025
$4.5M
Clinical Implications of Blood Pressure Patterns Among Older AdultsR01HL153191 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI JURASCHEK, STEPHEN P · 2021 to 2023
$2.3M
NHLBI NIH HHS R01 HL153191NHLBI NIH HHS R01 HL158622
6 · The paper itself

Abstract

Elevated blood pressure is one of the most important risk factors for cardiovascular disease (CVD). Despite blood pressure being historically measured in the supine position prior to the 20th century, current clinical guidelines are primarily based on seated measurements. Emerging evidence suggests that hypertension in the supine position may be equally or more strongly associated with cardiovascular risk and mortality than seated hypertension. However, there is no standardized protocol or diagnostic criteria to evaluate supine hypertension (SH) in the general population. Moreover, if SH is detected, clinical recommendations for its treatment remain unclear. In this review, we synthesized the literature on SH by conducting a MEDLINE search of publications from 2024 to 2025 and offer recommendations for the assessment, interpretation, and treatment of SH in the outpatient setting. In addition, we identify gaps in evidence and opportunities for future research to advance our understanding of this underappreciated and yet potent risk factor for cardiovascular disease.

Indexed as

Blood PressureCardiovascular DiseasesHypertensionBlood Pressure DeterminationHumansRisk FactorsSupine Positionautonomic dysfunctioncardiovascular diseasenocturnal blood pressureorthostatic hypotensionsupine blood pressureSupine hypertension

Identifiers

PMID40904320
PMCPMC12645888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.